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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RPA1_SCHPO (P15398)

Summary

This is the summary of UniProt entry RPA1_SCHPO (P15398).

Description: DNA-directed RNA polymerase I subunit rpa1 EC=2.7.7.6
Source organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (NCBI taxonomy ID 284812)
Length: 1689 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam RNA_pol_Rpb1_1 8 479
disorder n/a 153 154
disorder n/a 157 163
disorder n/a 267 289
low_complexity n/a 279 297
disorder n/a 294 304
disorder n/a 306 323
disorder n/a 372 383
low_complexity n/a 394 405
disorder n/a 406 408
disorder n/a 410 418
disorder n/a 445 463
Pfam RNA_pol_Rpb1_2 481 669
disorder n/a 535 540
disorder n/a 542 543
disorder n/a 616 618
disorder n/a 651 653
Pfam RNA_pol_Rpb1_3 672 848
Pfam RNA_pol_Rpb1_4 885 995
Pfam RNA_pol_Rpb1_5 1002 1634
low_complexity n/a 1107 1121
disorder n/a 1152 1153
disorder n/a 1156 1157
disorder n/a 1283 1287
disorder n/a 1346 1416
disorder n/a 1420 1441
low_complexity n/a 1423 1434

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P15398. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MNIAQPVSSE IKSVKFGIYD VDDVEKISVK QIVNPVLLDN LNHPTNGGLY
50
51
DLALGPYLKN SVCATCHLDE RYCPGHFGHI VLPIPAYHPL FFSQMYNLLR
100
101
STCLYCHHFK LSKVKVHLFF CRLKLLDYGL LNESEMVENV SLTEAIIKNS
150
151
NGTPLEDGSD SEDSGLGHDD IAKDAATLMR IRDEFVAKSI ADSRQNAHID
200
201
AQLTTLLLHE RKKVVRAFYH AISSRKQCDN CQSFSPNFRK EGFAKIFEIP
250
251
LSGKNLQFME QTGKIRSDVL RDTSKKHHED EGYDGDSDSS NESEVEGIDL
300
301
FEEDPNPLKN KSKSPIAHGA KYMTSTEVRN HLRRLFVKEN VVLSRLYAHK
350
351
RGKPASADMF FLQNIAVPPT RFRPASKMGD EVHENIQNEL LTRILQSSIQ
400
401
IASLSKDSTV EVNPDEKEGL ERRSRAFELL INAFVQLQHD VNSLIDSNRN
450
451
PSSGGQSRTV PPGIKQILEK KEGLFRKHMM GKRVNYAARS VISPDPNIET
500
501
NEIGVPPVFA TKLTYPEPVT LYNFNEMRNA VINGPHKWPG ASHIQNEDGT
550
551
LISLMPLTIE QRTALANQLL TPQSNLISSP YSYSRLINTN KKVYRHVRNG
600
601
DMLILNRQPT LHKPSMMAHK ARILPGEKTI RMHYANCNSY NADFDGDEMN
650
651
MHFPQSTNAR SEAQFIANTD SQYLVPTSGD PLRGLIQDHV VMGVWLTCKD
700
701
TFYTRDEYQQ LLFQALKPDE TGMYGRIKTL PPAIQRPGIY WTGKQIISSV
750
751
LLNLKPSDRP GLNLKSKAKV PGKYWSPDSE EGSVLFDDGE LLCGILDKSS
800
801
FGASAFGLVH SVHELYGPDI AGRLLSVLSR LFTAYAQMRG FTCRMDDLRL
850
851
DEQGDNWRRQ LLENGKSFGL EAASEYVGLS TDSPIALLNA NLEEVYRDDE
900
901
KLQGLDAAMK GKMNGLTSSI INKCIPDGLL TKFPYNHMQT MTVSGAKGSN
950
951
VNVSQISCLL GQQELEGRRV PLMVSGKSLP SFVPYETSAK SGGFIASRFL
1000
1001
TGIAPQEYYF HCMAGREGLI DTAVKTSRSG YLQRCLMKHL EGLCVQYDHT
1050
1051
VRDSDGSIVQ FHYGEDSLDV TKQKHLTQFE FSAKNYKSLI QKYKVKSVLS
1100
1101
AVDSETASSY AKKALKKPYK YDPVLDKYPP SRYLGSVSEK FQRAVDEYTQ
1150
1151
KNPDKLIASK KESKLDDSLL NESKFKALMQ LRYQQSLVDP GESVGVLASQ
1200
1201
SIGEPSTQMT LNTFHFAGFG AKNVTLGIPR LREIIMTASA NIQTPTMTLR
1250
1251
LNDGVSDKRA SAFCKEVNKL VLSEVVRQVR VTEKISGQGS DEQSKTYAIR
1300
1301
LDLYSRDEYQ DEYGVLQEEI ESTFSNRFLK ILNRIIKSYL AKSKQRKSGG
1350
1351
KDDTVPEVGQ ALKPLEDIDE APIEGRAQEA LEDEDNDATN EKMVSRSKQH
1400
1401
ASYEGPDEAD KVALRQLKGS NKVEDVNMDE EEDEGFKSDE SVSDFKERKL
1450
1451
LEKQNTVSIS ERRELQLKTA KEILSNCKHL DFDYVNGEWA TVELVFPINT
1500
1501
EKLLMVSLVE KACSETVIHE IPGITRCFSK PPDSALDTVP KVITEGVNLK
1550
1551
AIWEFYNEIS MNDIYTNDIA AILRIYGVEA ARNAIVHEVS SVFGVYGIAV
1600
1601
DPRHLSLIAD YMTFEGGYKA FNRMGIEYNT SPFAKMSFET TCHFLTEAAL
1650
1651
RGDVDDLSNP SSRLVVGRVG NFGTGSFDIF TPVVDSPAN            
1689
 

Show the unformatted sequence.

Checksums:
CRC64:2D2D3A2DEC94A497
MD5:e131c7626292b7f51c1769f86f63d433

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
RNA_pol_Rpb1_1 8 - 479 7AOC A 8 - 479 Show 3D Structure View in InterPro
7AOD A 8 - 479 Show 3D Structure View in InterPro
M 8 - 479 Show 3D Structure View in InterPro
7AOE A 8 - 479 Show 3D Structure View in InterPro
RNA_pol_Rpb1_2 481 - 669 7AOC A 481 - 669 Show 3D Structure View in InterPro
7AOD A 481 - 669 Show 3D Structure View in InterPro
M 481 - 669 Show 3D Structure View in InterPro
7AOE A 481 - 669 Show 3D Structure View in InterPro
RNA_pol_Rpb1_3 672 - 848 7AOC A 672 - 848 Show 3D Structure View in InterPro
7AOD A 672 - 848 Show 3D Structure View in InterPro
M 672 - 848 Show 3D Structure View in InterPro
7AOE A 672 - 848 Show 3D Structure View in InterPro
RNA_pol_Rpb1_4 885 - 995 7AOC A 885 - 995 Show 3D Structure View in InterPro
7AOD A 885 - 995 Show 3D Structure View in InterPro
M 885 - 995 Show 3D Structure View in InterPro
7AOE A 885 - 995 Show 3D Structure View in InterPro
RNA_pol_Rpb1_5 1002 - 1634 7AOC A 1002 - 1634 Show 3D Structure View in InterPro
7AOD A 1002 - 1634 Show 3D Structure View in InterPro
M 1002 - 1634 Show 3D Structure View in InterPro
7AOE A 1002 - 1634 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;