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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RPB1_CAEEL (P16356)

Summary

This is the summary of UniProt entry RPB1_CAEEL (P16356).

Description: DNA-directed RNA polymerase II subunit RPB1 EC=2.7.7.6
Source organism: Caenorhabditis elegans (NCBI taxonomy ID 6239)
Length: 1856 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam RNA_pol_Rpb1_1 12 348
disorder n/a 154 172
low_complexity n/a 154 172
low_complexity n/a 246 259
disorder n/a 276 277
disorder n/a 289 291
disorder n/a 323 336
Pfam RNA_pol_Rpb1_2 350 515
disorder n/a 436 437
Pfam RNA_pol_Rpb1_3 518 686
disorder n/a 600 602
disorder n/a 607 611
Pfam RNA_pol_Rpb1_4 711 817
disorder n/a 712 715
disorder n/a 718 719
disorder n/a 721 727
disorder n/a 730 731
disorder n/a 750 751
low_complexity n/a 761 772
Pfam RNA_pol_Rpb1_5 824 1419
Pfam RNA_pol_Rpb1_6 890 1073
disorder n/a 896 897
Pfam RNA_pol_Rpb1_7 1158 1291
disorder n/a 1262 1267
disorder n/a 1500 1509
Pfam RNA_pol_Rpb1_R 1502 1516
disorder n/a 1512 1513
disorder n/a 1515 1517
disorder n/a 1519 1525
disorder n/a 1527 1856
Pfam RNA_pol_Rpb1_R 1553 1571
Pfam RNA_pol_Rpb1_R 1580 1593
low_complexity n/a 1587 1605
Pfam RNA_pol_Rpb1_R 1594 1606
Pfam RNA_pol_Rpb1_R 1610 1623
low_complexity n/a 1610 1774
Pfam RNA_pol_Rpb1_R 1624 1637
Pfam RNA_pol_Rpb1_R 1638 1651
Pfam RNA_pol_Rpb1_R 1652 1665
Pfam RNA_pol_Rpb1_R 1673 1686
Pfam RNA_pol_Rpb1_R 1680 1693
Pfam RNA_pol_Rpb1_R 1687 1700
Pfam RNA_pol_Rpb1_R 1701 1714
Pfam RNA_pol_Rpb1_R 1721 1734
Pfam RNA_pol_Rpb1_R 1735 1748
Pfam RNA_pol_Rpb1_R 1749 1762
Pfam RNA_pol_Rpb1_R 1778 1789
low_complexity n/a 1778 1815
Pfam RNA_pol_Rpb1_R 1790 1803
Pfam RNA_pol_Rpb1_R 1798 1810
low_complexity n/a 1820 1852
Pfam RNA_pol_Rpb1_R 1839 1852

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P16356. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MALVGVDFQA PLRIVSRVQF GILGPEEIKR MSVAHVEFPE VYENGKPKLG
50
51
GLMDPRQGVI DRRGRCMTCA GNLTDCPGHF GHLELAKPVF HIGFLTKTLK
100
101
ILRCVCFYCG RLLIDKSAPR VLEILKKTGT NSKKRLTMIY DLCKAKSVCE
150
151
GAAEKEEGMP DDPDDPMNDG KKVAGGCGRY QPSYRRVGID INAEWKKNVN
200
201
EDTQERKIML TAERVLEVFQ QITDEDILVI GMDPQFARPE WMICTVLPVP
250
251
PLAVRPAVVT FGSAKNQDDL THKLSDIIKT NQQLQRNEAN GAAAHVLTDD
300
301
VRLLQFHVAT LVDNCIPGLP TATQKGGRPL KSIKQRLKGK EGRIRGNLMG
350
351
KRVDFSARTV ITADPNLPID TVGVPRTIAQ NLTFPEIVTP FNVDKLQELV
400
401
NRGDTQYPGA KYIIRENGAR VDLRYHPRAA DLHLQPGYRV ERHMKDGDII
450
451
VFNRQPTLHK MSMMGHRVKI LPWSTFRMNL SVTSPYNADF DGDEMNLHLP
500
501
QSLETRAEIE EIAMVPRQLI TPQANKPVMG IVQDTLCAVR MMTKRDVFID
550
551
WPFMMDLLMY LPTWDGKVPQ PAILKPKPLW TGKQVFSLII PGNVNVLRTH
600
601
STHPDSEDSG PYKWISPGDT KVIIEHGELL SGIVCSKTVG KSAGNLLHVV
650
651
TLELGYEIAA NFYSHIQTVI NAWLIREGHT IGIGDTIADQ ATYLDIQNTI
700
701
RKAKQDVVDV IEKAHNDDLE PTPGNTLRQT FENKVNQILN DARDRTGSSA
750
751
QKSLSEFNNF KSMVVSGSKG SKINISQVIA CVGQQNVEGK RIPFGFRHRT
800
801
LPHFIKDDYG PESKGFVENS YLAGLTPSEF FFHAMGGREG LIDTAVKTAE
850
851
TGYIQRRLIK AMESVMVNYD GTVRNSLAQM VQLRYGEDGL DGMWVENQNM
900
901
PTMKPNNAVF ERDFRMDLTD NKFLRKNYSE DVVREIQESE DGISLVESEW
950
951
SQLEEDRRLL RKIFPRGDAK IVLPCNLQRL IWNAQKIFKV DLRKPVNLSP
1000
1001
LHVISGVREL SKKLIIVSGN DEISKQAQYN ATLLMNILLR STLCTKNMCT
1050
1051
KSKLNSEAFD WLLGEIESRF QQAIAQPGEM VGALAAQSLG EPATQMTLNT
1100
1101
FHYAGVSAKN VTLGVPRLKE IINVSKTLKT PSLTVFLTGA AAKDPEKAKD
1150
1151
VLCKLEHTTL KKVTCNTAIY YDPDPKNTVI AEDEEWVSIF YEMPDHDLSR
1200
1201
TSPWLLRIEL DRKRMVDKKL TMEMIADRIH GGFGNDVHTI YTDDNAEKLV
1250
1251
FRLRIAGEDK GEAQEEQVDK MEDDVFLRCI EANMLSDLTL QGIPAISKVY
1300
1301
MNQPNTDDKK RIIITPEGGF KSVADWILET DGTALLRVLS ERQIDPVRTT
1350
1351
SNDICEIFEV LGIEAVRKAI EREMDNVISF DGSYVNYRHL ALLCDVMTAK
1400
1401
GHLMAITRHG INRQEVGALM RCSFEETVDI LMEAAVHAEE DPVKGVSENI
1450
1451
MLGQLARCGT GCFDLVLDVE KCKYGMEIPQ NVVMGGGFYG SFAGSPSNRE
1500
1501
FSPAHSPWNS GVTPTYAGAA WSPTTGGMSP GAGFSPAGNT DGGASPFNEG
1550
1551
GWSPASPGDP LGALSPRTPS YGGMSPGVYS PSSPQFSMTS PHYSPTSPSY
1600
1601
SPTSPAAGQS PVSPSYSPTS PSYSPTSPSY SPTSPSYSPT SPSYSPTSPS
1650
1651
YSPTSPSYSP SSPSYSPSSP SYSPSSPRYS PTSPTYSPTS PTYSPTSPTY
1700
1701
SPTSPTYSPT SPSYESGGGY SPSSPKYSPS SPTYSPTSPS YSPTSPQYSP
1750
1751
TSPQYSPSSP TYTPSSPTYN PTSPRGFSSP QYSPTSPTYS PTSPSYTPSS
1800
1801
PQYSPTSPTY TPSPSEQPGT SAQYSPTSPT YSPSSPTYSP ASPSYSPSSP
1850
1851
TYDPNS                                                
1856
 

Show the unformatted sequence.

Checksums:
CRC64:379BB183B957D2D5
MD5:63f063bb9d1ac08801dece40190ca052

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;