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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ICLR_ECOLI (P16528)

Summary

This is the summary of UniProt entry ICLR_ECOLI (P16528).

Description: Transcriptional repressor IclR {ECO:0000305}
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
View Pfam proteome data.
Length: 274 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 3
disorder n/a 8 21
Pfam HTH_IclR 26 77
disorder n/a 49 51
disorder n/a 57 61
disorder n/a 120 121
Pfam IclR 143 269

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P16528. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MVAPIPAKRG RKPAVATAPA TGQVQSLTRG LKLLEWIAES NGSVALTELA
50
51
QQAGLPNSTT HRLLTTMQQQ GFVRQVGELG HWAIGAHAFM VGSSFLQSRN
100
101
LLAIVHPILR NLMEESGETV NMAVLDQSDH EAIIIDQVQC THLMRMSAPI
150
151
GGKLPMHASG AGKAFLAQLS EEQVTKLLHR KGLHAYTHAT LVSPVHLKED
200
201
LAQTRKRGYS FDDEEHALGL RCLAACIFDE HREPFAAISI SGPISRITDD
250
251
RVTEFGAMVI KAAKEVTLAY GGMR                            
274
 

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Checksums:
CRC64:7C8A7E9FD2841D0C
MD5:1717022bae5763ebfa317e2ebce04a07

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
IclR 143 - 269 1TD5 A 49 - 175 Jmol OpenAstexViewer
B 49 - 175 Jmol OpenAstexViewer
C 49 - 175 Jmol OpenAstexViewer
D 49 - 175 Jmol OpenAstexViewer
2O99 A 49 - 175 Jmol OpenAstexViewer
B 49 - 175 Jmol OpenAstexViewer
C 49 - 175 Jmol OpenAstexViewer
D 49 - 175 Jmol OpenAstexViewer
2O9A A 49 - 175 Jmol OpenAstexViewer
B 49 - 175 Jmol OpenAstexViewer
C 49 - 175 Jmol OpenAstexViewer
D 49 - 175 Jmol OpenAstexViewer