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13  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MUTY_ECOLI (P17802)

Summary

This is the summary of UniProt entry MUTY_ECOLI (P17802).

Description: Adenine DNA glycosylase
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
Length: 350 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam HhH-GPD 35 170
Pfam HHH 99 128
Pfam EndIII_4Fe-2S 192 208
Pfam NUDIX_4 233 343

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P17802. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MQASQFSAQV LDWYDKYGRK TLPWQIDKTP YKVWLSEVML QQTQVATVIP
50
51
YFERFMARFP TVTDLANAPL DEVLHLWTGL GYYARARNLH KAAQQVATLH
100
101
GGKFPETFEE VAALPGVGRS TAGAILSLSL GKHFPILDGN VKRVLARCYA
150
151
VSGWPGKKEV ENKLWSLSEQ VTPAVGVERF NQAMMDLGAM ICTRSKPKCS
200
201
LCPLQNGCIA AANNSWALYP GKKPKQTLPE RTGYFLLLQH EDEVLLAQRP
250
251
PSGLWGGLYC FPQFADEESL RQWLAQRQIA ADNLTQLTAF RHTFSHFHLD
300
301
IVPMWLPVSS FTGCMDEGNA LWYNLAQPPS VGLAAPVERL LQQLRTGAPV
350
351
                                                      
350
 

Show the unformatted sequence.

Checksums:
CRC64:C7D3657C03EBBF4F
MD5:14cfebc4e74a61eff5be958fc20838ea

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
EndIII_4Fe-2S 192 - 208 1KG2 A 192 - 208 Show 3D Structure View in InterPro
1KG3 A 192 - 208 Show 3D Structure View in InterPro
1KG4 A 192 - 208 Show 3D Structure View in InterPro
1KG5 A 192 - 208 Show 3D Structure View in InterPro
1KG6 A 192 - 208 Show 3D Structure View in InterPro
1KG7 A 192 - 208 Show 3D Structure View in InterPro
1KQJ A 192 - 208 Show 3D Structure View in InterPro
1MUD A 192 - 208 Show 3D Structure View in InterPro
1MUN A 192 - 208 Show 3D Structure View in InterPro
1MUY A 192 - 208 Show 3D Structure View in InterPro
1WEF A 192 - 208 Show 3D Structure View in InterPro
1WEG A 192 - 208 Show 3D Structure View in InterPro
1WEI A 192 - 208 Show 3D Structure View in InterPro
HHH 99 - 128 1KG2 A 99 - 128 Show 3D Structure View in InterPro
1KG3 A 99 - 128 Show 3D Structure View in InterPro
1KG4 A 99 - 128 Show 3D Structure View in InterPro
1KG5 A 99 - 128 Show 3D Structure View in InterPro
1KG6 A 99 - 128 Show 3D Structure View in InterPro
1KG7 A 99 - 128 Show 3D Structure View in InterPro
1KQJ A 99 - 128 Show 3D Structure View in InterPro
1MUD A 99 - 128 Show 3D Structure View in InterPro
1MUN A 99 - 128 Show 3D Structure View in InterPro
1MUY A 99 - 128 Show 3D Structure View in InterPro
1WEF A 99 - 128 Show 3D Structure View in InterPro
1WEG A 99 - 128 Show 3D Structure View in InterPro
1WEI A 99 - 128 Show 3D Structure View in InterPro
HhH-GPD 35 - 170 1KG2 A 35 - 170 Show 3D Structure View in InterPro
1KG3 A 35 - 170 Show 3D Structure View in InterPro
1KG4 A 35 - 170 Show 3D Structure View in InterPro
1KG5 A 35 - 170 Show 3D Structure View in InterPro
1KG6 A 35 - 170 Show 3D Structure View in InterPro
1KG7 A 35 - 170 Show 3D Structure View in InterPro
1KQJ A 35 - 170 Show 3D Structure View in InterPro
1MUD A 35 - 170 Show 3D Structure View in InterPro
1MUN A 35 - 170 Show 3D Structure View in InterPro
1MUY A 35 - 170 Show 3D Structure View in InterPro
1WEF A 35 - 170 Show 3D Structure View in InterPro
1WEG A 35 - 170 Show 3D Structure View in InterPro
1WEI A 35 - 170 Show 3D Structure View in InterPro
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The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;