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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: EGLN_HUMAN (P17813)

Summary

This is the summary of UniProt entry EGLN_HUMAN (P17813).

Description: Endoglin
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 658 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
sig_p n/a 1 25
low_complexity n/a 4 24
disorder n/a 82 83
low_complexity n/a 94 106
disorder n/a 336 343
disorder n/a 345 346
Pfam Zona_pellucida 363 563
transmembrane n/a 587 614
low_complexity n/a 623 638
disorder n/a 625 632
disorder n/a 638 652
disorder n/a 655 658

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P17813. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDRGTLPLAV ALLLASCSLS PTSLAETVHC DLQPVGPERG EVTYTTSQVS
50
51
KGCVAQAPNA ILEVHVLFLE FPTGPSQLEL TLQASKQNGT WPREVLLVLS
100
101
VNSSVFLHLQ ALGIPLHLAY NSSLVTFQEP PGVNTTELPS FPKTQILEWA
150
151
AERGPITSAA ELNDPQSILL RLGQAQGSLS FCMLEASQDM GRTLEWRPRT
200
201
PALVRGCHLE GVAGHKEAHI LRVLPGHSAG PRTVTVKVEL SCAPGDLDAV
250
251
LILQGPPYVS WLIDANHNMQ IWTTGEYSFK IFPEKNIRGF KLPDTPQGLL
300
301
GEARMLNASI VASFVELPLA SIVSLHASSC GGRLQTSPAP IQTTPPKDTC
350
351
SPELLMSLIQ TKCADDAMTL VLKKELVAHL KCTITGLTFW DPSCEAEDRG
400
401
DKFVLRSAYS SCGMQVSASM ISNEAVVNIL SSSSPQRKKV HCLNMDSLSF
450
451
QLGLYLSPHF LQASNTIEPG QQSFVQVRVS PSVSEFLLQL DSCHLDLGPE
500
501
GGTVELIQGR AAKGNCVSLL SPSPEGDPRF SFLLHFYTVP IPKTGTLSCT
550
551
VALRPKTGSQ DQEVHRTVFM RLNIISPDLS GCTSKGLVLP AVLGITFGAF
600
601
LIGALLTAAL WYIYSHTRSP SKREPVVAVA APASSESSST NHSIGSTQST
650
651
PCSTSSMA                                              
658
 

Show the unformatted sequence.

Checksums:
CRC64:49CA2CE013298D17
MD5:a8ee20ef0bc127849fdd30d18a6d90cf

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.