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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: ARF4_HUMAN (P18085)

Summary

This is the summary of UniProt entry ARF4_HUMAN (P18085).

Description: ADP-ribosylation factor 4
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 180 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam Arf 5 177

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P18085. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGLTISSLFS RLFGKKQMRI LMVGLDAAGK TTILYKLKLG EIVTTIPTIG
50
51
FNVETVEYKN ICFTVWDVGG QDRIRPLWKH YFQNTQGLIF VVDSNDRERI
100
101
QEVADELQKM LLVDELRDAV LLLFANKQDL PNAMAISEMT DKLGLQSLRN
150
151
RTWYVQATCA TQGTGLYEGL DWLSNELSKR                      
180
 

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Checksums:
CRC64:3A43EB1F37A81BD9
MD5:0cf04532a28048d296a6f6056eb3e606

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Arf 5 - 177 1Z6X A 5 - 177 Jmol OpenAstexViewer
B 5 - 177 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.