Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: HB2I_MOUSE (P18468)

Summary

This is the summary of UniProt entry HB2I_MOUSE (P18468).

Description: H-2 class II histocompatibility antigen, I-A beta chain
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
View Pfam proteome data.
Length: 264 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
sig_p n/a 1 27
Pfam MHC_II_beta 40 114
Pfam C1-set 126 207
transmembrane n/a 226 248
low_complexity n/a 228 244

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P18468. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MVWLPRVPCV AAVILLLTVL SPPVALVRDS RPWFLEYCKS ECHFYNGTQR
50
51
VRFLKRYFYN LEENLRFDSD VGEFRAVTEL GRPDAENWNS QPEILDEKRA
100
101
AVDTYCRHNY EIFDNFLVPR RVEPTVTVYP TKTQPLEHHN LLVCSVSDFY
150
151
PGNIEVRWFR NGKEEKTGIV STGLVRNGDW TFQTLVMLET VPQSGEVYTC
200
201
QVEHPSLTDP VTVEWKAQST SAQNKMLSGV GGFVLGLLFL RAGLFIYFRN
250
251
QKGQSGLQPT GLLS                                       
264
 

Show the unformatted sequence.

Checksums:
CRC64:04529F5E2E527D7A
MD5:aad7af03003da85e20349b0a7cc21bd0

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
C1-set 126 - 207 1R5V B 126 - 207 Jmol OpenAstexViewer
D 126 - 207 Jmol OpenAstexViewer
MHC_II_beta 40 - 114 1R5V B 40 - 114 Jmol OpenAstexViewer
D 40 - 114 Jmol OpenAstexViewer