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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ANPRA_RAT (P18910)

Summary

This is the summary of UniProt entry ANPRA_RAT (P18910).

Description: Atrial natriuretic peptide receptor 1 EC=4.6.1.2
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 1057 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 28
low_complexity n/a 4 23
Pfam ANF_receptor 50 413
disorder n/a 283 284
disorder n/a 287 290
disorder n/a 293 295
disorder n/a 367 369
disorder n/a 371 372
disorder n/a 452 455
transmembrane n/a 470 490
low_complexity n/a 475 488
Pfam PK_Tyr_Ser-Thr 539 797
disorder n/a 751 756
disorder n/a 758 765
coiled_coil n/a 802 840
Pfam Guanylate_cyc 863 1049

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P18910. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPGSRRVRPR LRALLLLPPL LLLRGGHASD LTVAVVLPLT NTSYPWSWAR
50
51
VGPAVELALA RVKARPDLLP GWTVRMVLGS SENAAGVCSD TAAPLAAVDL
100
101
KWEHSPAVFL GPGCVYSAAP VGRFTAHWRV PLLTAGAPAL GIGVKDEYAL
150
151
TTRTGPSHVK LGDFVTALHR RLGWEHQALV LYADRLGDDR PCFFIVEGLY
200
201
MRVRERLNIT VNHQEFVEGD PDHYPKLLRA VRRKGRVIYI CSSPDAFRNL
250
251
MLLALNAGLT GEDYVFFHLD VFGQSLKSAQ GLVPQKPWER GDGQDRSARQ
300
301
AFQAAKIITY KEPDNPEYLE FLKQLKLLAD KKFNFTVEDG LKNIIPASFH
350
351
DGLLLYVQAV TETLAQGGTV TDGENITQRM WNRSFQGVTG YLKIDRNGDR
400
401
DTDFSLWDMD PETGAFRVVL NYNGTSQELM AVSEHKLYWP LGYPPPDVPK
450
451
CGFDNEDPAC NQDHFSTLEV LALVGSLSLI SFLIVSFFIY RKMQLEKELV
500
501
SELWRVRWED LQPSSLERHL RSAGSRLTLS GRGSNYGSLL TTEGQFQVFA
550
551
KTAYYKGNLV AVKRVNRKRI ELTRKVLFEL KHMRDVQNEH LTRFVGACTD
600
601
PPNICILTEY CPRGSLQDIL ENESITLDWM FRYSLTNDIV KGMLFLHNGA
650
651
ICSHGNLKSS NCVVDGRFVL KITDYGLESF RDPEPEQGHT LFAKKLWTAP
700
701
ELLRMASPPA RGSQAGDVYS FGIILQEIAL RSGVFYVEGL DLSPKEIIER
750
751
VTRGEQPPFR PSMDLQSHLE ELGQLMQRCW AEDPQERPPF QQIRLALRKF
800
801
NKENSSNILD NLLSRMEQYA NNLEELVEER TQAYLEEKRK AEALLYQILP
850
851
HSVAEQLKRG ETVQAEAFDS VTIYFSDIVG FTALSAESTP MQVVTLLNDL
900
901
YTCFDAVIDN FDVYKVETIG DAYMVVSGLP VRNGQLHARE VARMALALLD
950
951
AVRSFRIRHR PQEQLRLRIG IHTGPVCAGV VGLKMPRYCL FGDTVNTASR
1000
1001
MESNGEALKI HLSSETKAVL EEFDGFELEL RGDVEMKGKG KVRTYWLLGE
1050
1051
RGCSTRG                                               
1057
 

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Checksums:
CRC64:9EA9AE685AC05816
MD5:17a7199113ec2e9fb3bd029e253cd4fb

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
ANF_receptor 50 - 413 1DP4 A 22 - 385 Jmol OpenAstexViewer
C 22 - 385 Jmol OpenAstexViewer
1T34 A 22 - 385 Jmol OpenAstexViewer
B 22 - 385 Jmol OpenAstexViewer
3A3K A 22 - 385 Jmol OpenAstexViewer
B 22 - 385 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.