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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SDHL_HUMAN (P20132)

Summary

This is the summary of UniProt entry SDHL_HUMAN (P20132).

Description: L-serine dehydratase/L-threonine deaminase EC=4.3.1.17 EC=4.3.1.19
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 328 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam PALP 5 304
low_complexity n/a 64 75
low_complexity n/a 164 183

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P20132. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MMSGEPLHVK TPIRDSMALS KMAGTSVYLK MDSAQPSGSF KIRGIGHFCK
50
51
RWAKQGCAHF VCSSAGNAGM AAAYAARQLG VPATIVVPST TPALTIERLK
100
101
NEGATVKVVG ELLDEAFELA KALAKNNPGW VYIPPFDDPL IWEGHASIVK
150
151
ELKETLWEKP GAIALSVGGG GLLCGVVQGL QEVGWGDVPV IAMETFGAHS
200
201
FHAATTAGKL VSLPKITSVA KALGVKTVGA QALKLFQEHP IFSEVISDQE
250
251
AVAAIEKFVD DEKILVEPAC GAALAAVYSH VIQKLQLEGN LRTPLPSLVV
300
301
IVCGGSNISL AQLRALKEQL GMTNRLPK                        
328
 

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Checksums:
CRC64:F6E9AB01D6308C83
MD5:1d6744fd2cc00d62ae3fef741977f072

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
PALP 5 - 304 1P5J A 5 - 304 Jmol OpenAstexViewer
4H27 A 5 - 304 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.