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6  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: IF2A_YEAST (P20459)

Summary

This is the summary of UniProt entry IF2A_YEAST (P20459).

Description: Eukaryotic translation initiation factor 2 subunit alpha
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (NCBI taxonomy ID 559292)
View Pfam proteome data.
Length: 304 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam S1 13 88
low_complexity n/a 45 58
Pfam EIF_2_alpha 126 237
disorder n/a 275 277
disorder n/a 282 304
low_complexity n/a 291 303

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P20459. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSTSHCRFYE NKYPEIDDIV MVNVQQIAEM GAYVKLLEYD NIEGMILLSE
50
51
LSRRRIRSIQ KLIRVGKNDV AVVLRVDKEK GYIDLSKRRV SSEDIIKCEE
100
101
KYQKSKTVHS ILRYCAEKFQ IPLEELYKTI AWPLSRKFGH AYEAFKLSII
150
151
DETVWEGIEP PSKDVLDELK NYISKRLTPQ AVKIRADVEV SCFSYEGIDA
200
201
IKDALKSAED MSTEQMQVKV KLVAAPLYVL TTQALDKQKG IEQLESAIEK
250
251
ITEVITKYGG VCNITMPPKA VTATEDAELQ ALLESKELDN RSDSEDDEDE
300
301
SDDE                                                  
304
 

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Checksums:
CRC64:AF4F1C80303A4E98
MD5:06b594b2c48f8dd9957a95871dfe0583

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
EIF_2_alpha 126 - 175 2A19 A 125 - 174 Jmol OpenAstexViewer
126 - 176 1Q46 A 125 - 175 Jmol OpenAstexViewer
2A1A A 125 - 175 Jmol OpenAstexViewer
126 - 237 3J81 j 126 - 237 Jmol OpenAstexViewer
3JAP j 126 - 237 Jmol OpenAstexViewer
3JAQ j 126 - 237 Jmol OpenAstexViewer
S1 13 - 88 1Q46 A 12 - 87 Jmol OpenAstexViewer
2A19 A 12 - 87 Jmol OpenAstexViewer
2A1A A 12 - 87 Jmol OpenAstexViewer
3J81 j 13 - 88 Jmol OpenAstexViewer
3JAP j 13 - 88 Jmol OpenAstexViewer
3JAQ j 13 - 88 Jmol OpenAstexViewer