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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CP3A5_HUMAN (P20815)

Summary

This is the summary of UniProt entry CP3A5_HUMAN (P20815).

Description: Cytochrome P450 3A5 EC=1.14.14.1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 502 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
transmembrane n/a 6 25
low_complexity n/a 12 24
low_complexity n/a 35 47
Pfam p450 38 492
low_complexity n/a 214 228
transmembrane n/a 215 233
disorder n/a 334 335
disorder n/a 412 414
disorder n/a 501 502

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P20815. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDLIPNLAVE TWLLLAVSLV LLYLYGTRTH GLFKRLGIPG PTPLPLLGNV
50
51
LSYRQGLWKF DTECYKKYGK MWGTYEGQLP VLAITDPDVI RTVLVKECYS
100
101
VFTNRRSLGP VGFMKSAISL AEDEEWKRIR SLLSPTFTSG KLKEMFPIIA
150
151
QYGDVLVRNL RREAEKGKPV TLKDIFGAYS MDVITGTSFG VNIDSLNNPQ
200
201
DPFVESTKKF LKFGFLDPLF LSIILFPFLT PVFEALNVSL FPKDTINFLS
250
251
KSVNRMKKSR LNDKQKHRLD FLQLMIDSQN SKETESHKAL SDLELAAQSI
300
301
IFIFAGYETT SSVLSFTLYE LATHPDVQQK LQKEIDAVLP NKAPPTYDAV
350
351
VQMEYLDMVV NETLRLFPVA IRLERTCKKD VEINGVFIPK GSMVVIPTYA
400
401
LHHDPKYWTE PEEFRPERFS KKKDSIDPYI YTPFGTGPRN CIGMRFALMN
450
451
MKLALIRVLQ NFSFKPCKET QIPLKLDTQG LLQPEKPIVL KVDSRDGTLS
500
501
GE                                                    
502
 

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Checksums:
CRC64:D5A2302E2633E717
MD5:dd36da70ca28d8e81f18ff7b80d32870

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.