Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PTFBC_ECOLI (P20966)

Summary

This is the summary of UniProt entry PTFBC_ECOLI (P20966).

Description: PTS system fructose-specific EIIB'BC component {ECO:0000305|PubMed:8626640} PTS system fructose-specific EIIB component {ECO:0000303|PubMed:3076173} PTS system fructose-specific EIIC component {ECO:0000303|PubMed:3076173}
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
Length: 563 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
low_complexity n/a 89 100
Pfam PTS_IIB 107 198
low_complexity n/a 154 171
disorder n/a 207 215
disorder n/a 217 218
transmembrane n/a 230 256
Pfam PTS_EIIC 231 496
transmembrane n/a 268 291
transmembrane n/a 303 329
low_complexity n/a 313 330
low_complexity n/a 346 358
transmembrane n/a 349 368
transmembrane n/a 389 410
transmembrane n/a 430 451
transmembrane n/a 463 482
transmembrane n/a 488 507
transmembrane n/a 519 551

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P20966. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKTLLIIDAN LGQARAYMAK TLLGAAARKA KLEIIDNPND AEMAIVLGDS
50
51
IPNDSALNGK NVWLGDISRA VAHPELFLSE AKGHAKPYTA PVAATAPVAA
100
101
SGPKRVVAVT ACPTGVAHTF MAAEAIETEA KKRGWWVKVE TRGSVGAGNA
150
151
ITPEEVAAAD LVIVAADIEV DLAKFAGKPM YRTSTGLALK KTAQELDKAV
200
201
AEATPYEPAG KAQTATTESK KESAGAYRHL LTGVSYMLPM VVAGGLCIAL
250
251
SFAFGIEAFK EPGTLAAALM QIGGGSAFAL MVPVLAGYIA FSIADRPGLT
300
301
PGLIGGMLAV STGSGFIGGI IAGFLAGYIA KLISTQLKLP QSMEALKPIL
350
351
IIPLISSLVV GLAMIYLIGK PVAGILEGLT HWLQTMGTAN AVLLGAILGG
400
401
MMCTDMGGPV NKAAYAFGVG LLSTQTYGPM AAIMAAGMVP PLAMGLATMV
450
451
ARRKFDKAQQ EGGKAALVLG LCFISEGAIP FAARDPMRVL PCCIVGGALT
500
501
GAISMAIGAK LMAPHGGLFV LLIPGAITPV LGYLVAIIAG TLVAGLAYAF
550
551
LKRPEVDAVA KAA                                        
563
 

Show the unformatted sequence.

Checksums:
CRC64:AC066A96A94DBA05
MD5:3e4c32d28b0bea753a45d03181153eea

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;