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13  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: AP1G1_MOUSE (P22892)

Summary

This is the summary of UniProt entry AP1G1_MOUSE (P22892).

Description: AP-1 complex subunit gamma-1
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 822 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
low_complexity n/a 5 19
Pfam Adaptin_N 23 574
low_complexity n/a 248 258
disorder n/a 584 587
disorder n/a 590 629
low_complexity n/a 626 636
disorder n/a 639 649
disorder n/a 651 653
low_complexity n/a 653 667
disorder n/a 668 679
low_complexity n/a 668 676
disorder n/a 681 685
Pfam Alpha_adaptinC2 705 817
disorder n/a 731 733
low_complexity n/a 759 771

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P22892. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPAPIRLREL IRTIRTARTQ AEEREMIQKE CAAIRSSFRE EDNTYRCRNV
50
51
AKLLYMHMLG YPAHFGQLEC LKLIASQKFT DKRIGYLGAM LLLDERQDVH
100
101
LLMTNCIKND LNHSTQFVQG LALCTLGCMG SSEMCRDLAG EVEKLLKTSN
150
151
SYLRKKAALC AVHVIRKVPE LMEMFLPATK NLLNEKNHGV LHTSVVLLTE
200
201
MCERSPDMLA HFRKLVPQLV RILKNLIMSG YSPEHDVSGI SDPFLQVRIL
250
251
RLLRILGRND DDSSEAMNDI LAQVATNTET SKNVGNAILY ETVLTIMDIK
300
301
SESGLRVLAI NILGRFLLNN DKNIRYVALT SLLKTVQTDH NAVQRHRSTI
350
351
VDCLKDLDVS IKRRAMELSF ALVNGNNIRG MMKELLYFLD SCEPEFKADC
400
401
ASGIFLAAEK YAPSKRWHID TIMRVLTTAG SYVRDDAVPN LIQLITNSVE
450
451
MHAYTVQRLY KAILGDYSQQ PLVQVAAWCI GEYGDLLVSG QCEEEEPIQV
500
501
TEDEVLDILE SVLISNMSTS VTRGYALTAI MKLSTRFTCT VNRIKKVVSI
550
551
YGSSIDVELQ QRAVEYNALF KKYDHMRSAL LERMPVMEKV TTNGPSEIVQ
600
601
TNGETEPAPL ETKPPPSGPQ PTSQANDLLD LLGGNDITPV IPTAPTSKPA
650
651
SAGGELLDLL GDITLTGAPA AAPTPASVPQ ISQPPFLLDG LSSQPLFNDI
700
701
APGIPSITAY SKNGLKIEFT FERSNTNPSV TVITIQASNS TELDMTDFVF
750
751
QAAVPKTFQL QLLSPSSSVV PAFNTGTITQ VIKVLNPQKQ QLRMRIKLTY
800
801
NHKGSAMQDL AEVNNFPPQS WQ                              
822
 

Show the unformatted sequence.

Checksums:
CRC64:15317E4BCD9503EB
MD5:41c80a8824ae6d4a7abaf07245173f51

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Adaptin_N 23 - 574 1W63 A 23 - 574 Show 3D Structure View in InterPro
C 23 - 574 Show 3D Structure View in InterPro
E 23 - 574 Show 3D Structure View in InterPro
G 23 - 574 Show 3D Structure View in InterPro
I 23 - 574 Show 3D Structure View in InterPro
K 23 - 574 Show 3D Structure View in InterPro
4HMY A 23 - 574 Show 3D Structure View in InterPro
4P6Z G 23 - 574 Show 3D Structure View in InterPro
6CM9 G 23 - 574 Show 3D Structure View in InterPro
6CRI G 23 - 574 Show 3D Structure View in InterPro
Q 23 - 574 Show 3D Structure View in InterPro
R 23 - 574 Show 3D Structure View in InterPro
6D83 G 23 - 574 Show 3D Structure View in InterPro
6D84 G 23 - 574 Show 3D Structure View in InterPro
K 23 - 574 Show 3D Structure View in InterPro
6DFF G 23 - 574 Show 3D Structure View in InterPro
Alpha_adaptinC2 705 - 817 1GYU A 705 - 817 Show 3D Structure View in InterPro
1GYV A 705 - 817 Show 3D Structure View in InterPro
1GYW A 705 - 817 Show 3D Structure View in InterPro
B 705 - 817 Show 3D Structure View in InterPro
2A7B A 705 - 817 Show 3D Structure View in InterPro
3ZY7 A 3 - 115 Show 3D Structure View in InterPro
B 3 - 115 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;