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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SC6A2_HUMAN (P23975)

Summary

This is the summary of UniProt entry SC6A2_HUMAN (P23975).

Description: Sodium-dependent noradrenaline transporter
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 617 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 9 23
Pfam SNF 56 580
transmembrane n/a 65 83
transmembrane n/a 95 116
transmembrane n/a 137 164
transmembrane n/a 232 250
low_complexity n/a 236 247
transmembrane n/a 262 287
transmembrane n/a 307 332
transmembrane n/a 344 369
transmembrane n/a 389 415
transmembrane n/a 444 469
transmembrane n/a 475 498
transmembrane n/a 519 538
transmembrane n/a 558 578

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P23975. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MLLARMNPQV QPENNGADTG PEQPLRARKT AELLVVKERN GVQCLLAPRD
50
51
GDAQPRETWG KKIDFLLSVV GFAVDLANVW RFPYLCYKNG GGAFLIPYTL
100
101
FLIIAGMPLF YMELALGQYN REGAATVWKI CPFFKGVGYA VILIALYVGF
150
151
YYNVIIAWSL YYLFSSFTLN LPWTDCGHTW NSPNCTDPKL LNGSVLGNHT
200
201
KYSKYKFTPA AEFYERGVLH LHESSGIHDI GLPQWQLLLC LMVVVIVLYF
250
251
SLWKGVKTSG KVVWITATLP YFVLFVLLVH GVTLPGASNG INAYLHIDFY
300
301
RLKEATVWID AATQIFFSLG AGFGVLIAFA SYNKFDNNCY RDALLTSSIN
350
351
CITSFVSGFA IFSILGYMAH EHKVNIEDVA TEGAGLVFIL YPEAISTLSG
400
401
STFWAVVFFV MLLALGLDSS MGGMEAVITG LADDFQVLKR HRKLFTFGVT
450
451
FSTFLLALFC ITKGGIYVLT LLDTFAAGTS ILFAVLMEAI GVSWFYGVDR
500
501
FSNDIQQMMG FRPGLYWRLC WKFVSPAFLL FVVVVSIINF KPLTYDDYIF
550
551
PPWANWVGWG IALSSMVLVP IYVIYKFLST QGSLWERLAY GITPENEHHL
600
601
VAQRDIRQFQ LQHWLAI                                    
617
 

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Checksums:
CRC64:BDC6DF31316907BB
MD5:166415c5ccb5a8ca568bbe42c89320f4

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.