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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: EF1B_HUMAN (P24534)

Summary

This is the summary of UniProt entry EF1B_HUMAN (P24534).

Description: Elongation factor 1-beta
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 225 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 36 37
disorder n/a 80 121
low_complexity n/a 85 107
Pfam EF-1_beta_acid 103 130
low_complexity n/a 105 123
coiled_coil n/a 109 129
Pfam EF1_GNE 141 225

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P24534. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGFGDLKSPA GLQVLNDYLA DKSYIEGYVP SQADVAVFEA VSSPPPADLC
50
51
HALRWYNHIK SYEKEKASLP GVKKALGKYG PADVEDTTGS GATDSKDDDD
100
101
IDLFGSDDEE ESEEAKRLRE ERLAQYESKK AKKPALVAKS SILLDVKPWD
150
151
DETDMAKLEE CVRSIQADGL VWGSSKLVPV GYGIKKLQIQ CVVEDDKVGT
200
201
DMLEEQITAF EDYVQSMDVA AFNKI                           
225
 

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Checksums:
CRC64:CDE763ADBF127822
MD5:bf326f0075594c63969b4a8df62b4bb3

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
EF1_GNE 141 - 225 1B64 A 7 - 91 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.