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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ADA1D_HUMAN (P25100)

Summary

This is the summary of UniProt entry ADA1D_HUMAN (P25100).

Description: Alpha-1D adrenergic receptor
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 572 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 5 47
low_complexity n/a 17 61
disorder n/a 54 76
low_complexity n/a 66 78
transmembrane n/a 99 121
Pfam 7tm_1 113 402
transmembrane n/a 133 152
transmembrane n/a 172 192
low_complexity n/a 212 232
transmembrane n/a 213 234
transmembrane n/a 254 279
low_complexity n/a 267 281
transmembrane n/a 346 366
transmembrane n/a 386 405
low_complexity n/a 410 431
disorder n/a 447 452
low_complexity n/a 449 478
disorder n/a 460 488
disorder n/a 511 521
low_complexity n/a 521 535
disorder n/a 524 534
disorder n/a 536 547

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P25100. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTFRDLLSVS FEGPRPDSSA GGSSAGGGGG SAGGAAPSEG PAVGGVPGGA
50
51
GGGGGVVGAG SGEDNRSSAG EPGSAGAGGD VNGTAAVGGL VVSAQGVGVG
100
101
VFLAAFILMA VAGNLLVILS VACNRHLQTV TNYFIVNLAV ADLLLSATVL
150
151
PFSATMEVLG FWAFGRAFCD VWAAVDVLCC TASILSLCTI SVDRYVGVRH
200
201
SLKYPAIMTE RKAAAILALL WVVALVVSVG PLLGWKEPVP PDERFCGITE
250
251
EAGYAVFSSV CSFYLPMAVI VVMYCRVYVV ARSTTRSLEA GVKRERGKAS
300
301
EVVLRIHCRG AATGADGAHG MRSAKGHTFR SSLSVRLLKF SREKKAAKTL
350
351
AIVVGVFVLC WFPFFFVLPL GSLFPQLKPS EGVFKVIFWL GYFNSCVNPL
400
401
IYPCSSREFK RAFLRLLRCQ CRRRRRRRPL WRVYGHHWRA STSGLRQDCA
450
451
PSSGDAPPGA PLALTALPDP DPEPPGTPEM QAPVASRRKP PSAFREWRLL
500
501
GPFRRPTTQL RAKVSSLSHK IRAGGAQRAE AACAQRSEVE AVSLGVPHEV
550
551
AEGATCQAYE LADYSNLRET DI                              
572
 

Show the unformatted sequence.

Checksums:
CRC64:EBEB134CF20A4988
MD5:ded742346f60b559b3a764abfc6fb708

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.