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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MCM3_HUMAN (P25205)

Summary

This is the summary of UniProt entry MCM3_HUMAN (P25205).

Description: DNA replication licensing factor MCM3 EC=3.6.4.12
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 808 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam MCM_N 13 122
Pfam MCM_OB 110 245
disorder n/a 178 180
disorder n/a 185 187
disorder n/a 203 207
low_complexity n/a 216 226
Pfam MCM 280 505
disorder n/a 377 381
disorder n/a 497 506
disorder n/a 508 515
disorder n/a 518 522
disorder n/a 529 533
disorder n/a 535 551
Pfam MCM_lid 566 653
disorder n/a 592 621
disorder n/a 632 639
coiled_coil n/a 655 680
low_complexity n/a 658 694
disorder n/a 662 738
disorder n/a 762 788
disorder n/a 791 792

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P25205. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAGTVVLDDV ELREAQRDYL DFLDDEEDQG IYQSKVRELI SDNQYRLIVN
50
51
VNDLRRKNEK RANRLLNNAF EELVAFQRAL KDFVASIDAT YAKQYEEFYV
100
101
GLEGSFGSKH VSPRTLTSCF LSCVVCVEGI VTKCSLVRPK VVRSVHYCPA
150
151
TKKTIERRYS DLTTLVAFPS SSVYPTKDEE NNPLETEYGL SVYKDHQTIT
200
201
IQEMPEKAPA GQLPRSVDVI LDDDLVDKAK PGDRVQVVGT YRCLPGKKGG
250
251
YTSGTFRTVL IACNVKQMSK DAQPSFSAED IAKIKKFSKT RSKDIFDQLA
300
301
KSLAPSIHGH DYVKKAILCL LLGGVERDLE NGSHIRGDIN ILLIGDPSVA
350
351
KSQLLRYVLC TAPRAIPTTG RGSSGVGLTA AVTTDQETGE RRLEAGAMVL
400
401
ADRGVVCIDE FDKMSDMDRT AIHEVMEQGR VTIAKAGIHA RLNARCSVLA
450
451
AANPVYGRYD QYKTPMENIG LQDSLLSRFD LLFIMLDQMD PEQDREISDH
500
501
VLRMHRYRAP GEQDGDAMPL GSAVDILATD DPNFSQEDQQ DTQIYEKHDN
550
551
LLHGTKKKKE KMVSAAFMKK YIHVAKIIKP VLTQESATYI AEEYSRLRSQ
600
601
DSMSSDTART SPVTARTLET LIRLATAHAK ARMSKTVDLQ DAEEAVELVQ
650
651
YAYFKKVLEK EKKRKKRSED ESETEDEEEK SQEDQEQKRK RRKTRQPDAK
700
701
DGDSYDPYDF SDTEEEMPQV HTPKTADSQE TKESQKVELS ESRLKAFKVA
750
751
LLDVFREAHA QSIGMNRLTE SINRDSEEPF SSVEIQAALS KMQDDNQVMV
800
801
SEGIIFLI                                              
808
 

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Checksums:
CRC64:C967C068B7090558
MD5:2e7950a61fa2bc6b54dd920c4cd5b13e

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.