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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: LIGB_ECOLI (P25772)

Summary

This is the summary of UniProt entry LIGB_ECOLI (P25772).

Description: DNA ligase B EC=6.5.1.2
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
Length: 560 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
sig_p n/a 1 20
Pfam DNA_ligase_aden 98 308
disorder n/a 145 146
Pfam DNA_ligase_OB 311 389
disorder n/a 382 385

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P25772. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKVWMAILIG ILCWQSSVWA VCPAWSPARA QEEISRLQQQ IKQWDDDYWK
50
51
EGKSEVEDGV YDQLSARLTQ WQRCFGSEPR DVMMPPLNGA VMHPVAHTGV
100
101
RKMVDKNALS LWMRERSDLW VQPKVDGVAV TLVYRDGKLN KAISRGNGLK
150
151
GEDWTQKVSL ISAVPQTVSG PLANSTLQGE IFLQREGHIQ QQMGGINARA
200
201
KVAGLMMRQD DSDTLNSLGV FVWAWPDGPQ LMSDRLKELA TAGFTLTQTY
250
251
TRAVKNADEV ARVRNEWWKA ELPFVTDGVV VRAAKEPESR HWLPGQAEWL
300
301
VAWKYQPVAQ VAEVKAIQFA VGKSGKISVV ASLAPVMLDD KKVQRVNIGS
350
351
VRRWQEWDIA PGDQILVSLA GQGIPRIDDV VWRGAERTKP TPPENRFNSL
400
401
TCYFASDVCQ EQFISRLVWL GAKQVLGLDG IGEAGWRALH QTHRFEHIFS
450
451
WLLLTPEQLQ NTPGIAKSKS AQLWHQFNLA RKQPFTRWVM AMGIPLTRAA
500
501
LNASDERSWS QLLFSTEQFW QQLPGTGSGR ARQVIEWKEN AQIKKLGSWL
550
551
AAQQITGFEP                                            
560
 

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Checksums:
CRC64:2C1BA1F9B247A599
MD5:cce2618bcee96562c964ed9b740fb9fa

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;