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54  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HPPK_ECOLI (P26281)

Summary

This is the summary of UniProt entry HPPK_ECOLI (P26281).

Description: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase EC=2.7.6.3
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
View Pfam proteome data.
Length: 159 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam HPPK 5 134
disorder n/a 52 53

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P26281. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTVAYIAIGS NLASPLEQVN AALKALGDIP ESHILTVSSF YRTPPLGPQD
50
51
QPDYLNAAVA LETSLAPEEL LNHTQRIELQ QGRVRKAERW GPRTLDLDIM
100
101
LFGNEVINTE RLTVPHYDMK NRGFMLWPLF EIAPELVFPD GEMLRQILHT
150
151
RAFDKLNKW                                             
159
 

Show the unformatted sequence.

Checksums:
CRC64:67301CD634D0A174
MD5:8ec3f596357e83c64d4a301a0a64841c

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
HPPK 5 - 134 1DY3 A 4 - 133 Jmol OpenAstexViewer
1EQ0 A 4 - 133 Jmol OpenAstexViewer
1EQM A 4 - 133 Jmol OpenAstexViewer
1EX8 A 4 - 133 Jmol OpenAstexViewer
1F9H A 4 - 133 Jmol OpenAstexViewer
1G4C A 4 - 133 Jmol OpenAstexViewer
B 204 - 333 Jmol OpenAstexViewer
1HKA A 4 - 133 Jmol OpenAstexViewer
1HQ2 A 4 - 133 Jmol OpenAstexViewer
1IM6 A 4 - 133 Jmol OpenAstexViewer
1KBR A 4 - 133 Jmol OpenAstexViewer
1Q0N A 4 - 133 Jmol OpenAstexViewer
1RAO A 4 - 133 Jmol OpenAstexViewer
1RB0 A 4 - 133 Jmol OpenAstexViewer
1RTZ A 4 - 133 Jmol OpenAstexViewer
1RU1 A 4 - 133 Jmol OpenAstexViewer
B 204 - 333 Jmol OpenAstexViewer
1RU2 A 4 - 133 Jmol OpenAstexViewer
1TMJ A 4 - 133 Jmol OpenAstexViewer
1TMM A 4 - 133 Jmol OpenAstexViewer
B 204 - 333 Jmol OpenAstexViewer
2F63 A 4 - 133 Jmol OpenAstexViewer
2F65 A 4 - 133 Jmol OpenAstexViewer
3HCX A 4 - 133 Jmol OpenAstexViewer
3HD1 A 4 - 133 Jmol OpenAstexViewer
3HD2 A 4 - 133 Jmol OpenAstexViewer
3HSD A 4 - 133 Jmol OpenAstexViewer
B 4 - 133 Jmol OpenAstexViewer
3HSG A 4 - 133 Jmol OpenAstexViewer
3HSJ A 4 - 133 Jmol OpenAstexViewer
3HSZ A 4 - 133 Jmol OpenAstexViewer
3HT0 A 4 - 133 Jmol OpenAstexViewer
3ILI A 4 - 133 Jmol OpenAstexViewer
3ILJ A 4 - 133 Jmol OpenAstexViewer
3ILL A 4 - 133 Jmol OpenAstexViewer
3ILO A 4 - 133 Jmol OpenAstexViewer
3IP0 A 4 - 133 Jmol OpenAstexViewer
3KUE A 4 - 133 Jmol OpenAstexViewer
3KUG A 4 - 133 Jmol OpenAstexViewer
3KUH A 4 - 133 Jmol OpenAstexViewer
3UD5 A 4 - 133 Jmol OpenAstexViewer
3UDE A 4 - 133 Jmol OpenAstexViewer
3UDV A 4 - 133 Jmol OpenAstexViewer
4F7V A 4 - 133 Jmol OpenAstexViewer
4M5G A 4 - 133 Jmol OpenAstexViewer
4M5H A 4 - 133 Jmol OpenAstexViewer
4M5I A 4 - 133 Jmol OpenAstexViewer
4M5J A 4 - 133 Jmol OpenAstexViewer
4M5K A 4 - 133 Jmol OpenAstexViewer
4M5L A 4 - 133 Jmol OpenAstexViewer
4M5M A 4 - 133 Jmol OpenAstexViewer
4M5N A 4 - 133 Jmol OpenAstexViewer
B 4 - 133 Jmol OpenAstexViewer
5ETK A 4 - 133 Jmol OpenAstexViewer
5ETL A 4 - 133 Jmol OpenAstexViewer
B 4 - 133 Jmol OpenAstexViewer
C 4 - 133 Jmol OpenAstexViewer
D 4 - 133 Jmol OpenAstexViewer
5ETM A 4 - 133 Jmol OpenAstexViewer
5ETN A 4 - 133 Jmol OpenAstexViewer
5ETO A 4 - 133 Jmol OpenAstexViewer
5ETP A 4 - 133 Jmol OpenAstexViewer