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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: EF1G_HUMAN (P26641)

Summary

This is the summary of UniProt entry EF1G_HUMAN (P26641).

Description: Elongation factor 1-gamma
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 437 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam GST_N 2 81
Pfam GST_C 106 198
disorder n/a 221 271
low_complexity n/a 237 261
Pfam EF1G 275 381

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P26641. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAAGTLYTYP ENWRAFKALI AAQYSGAQVR VLSAPPHFHF GQTNRTPEFL
50
51
RKFPAGKVPA FEGDDGFCVF ESNAIAYYVS NEELRGSTPE AAAQVVQWVS
100
101
FADSDIVPPA STWVFPTLGI MHHNKQATEN AKEEVRRILG LLDAYLKTRT
150
151
FLVGERVTLA DITVVCTLLW LYKQVLEPSF RQAFPNTNRW FLTCINQPQF
200
201
RAVLGEVKLC EKMAQFDAKK FAETQPKKDT PRKEKGSREE KQKPQAERKE
250
251
EKKAAAPAPE EEMDECEQAL AAEPKAKDPF AHLPKSTFVL DEFKRKYSNE
300
301
DTLSVALPYF WEHFDKDGWS LWYSEYRFPE ELTQTFMSCN LITGMFQRLD
350
351
KLRKNAFASV ILFGTNNSSS ISGVWVFRGQ ELAFPLSPDW QVDYESYTWR
400
401
KLDPGSEETQ TLVREYFSWE GAFQHVGKAF NQGKIFK              
437
 

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Checksums:
CRC64:A6110663110CF3FC
MD5:632fe40d54dba2c003b49d3a8be9a8e2

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
EF1G 276 - 381 1PBU A 276 - 381 Jmol OpenAstexViewer
GST_C 106 - 198 5DQS A 106 - 198 Jmol OpenAstexViewer
5JPO A 106 - 198 Jmol OpenAstexViewer
B 106 - 198 Jmol OpenAstexViewer
C 106 - 198 Jmol OpenAstexViewer
D 106 - 198 Jmol OpenAstexViewer
GST_N 2 - 81 5DQS A 2 - 81 Jmol OpenAstexViewer
5JPO A 2 - 81 Jmol OpenAstexViewer
B 2 - 81 Jmol OpenAstexViewer
C 2 - 81 Jmol OpenAstexViewer
D 2 - 81 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.