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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: THIK_YEAST (P27796)

Summary

This is the summary of UniProt entry THIK_YEAST (P27796).

Description: 3-ketoacyl-CoA thiolase, peroxisomal EC=2.3.1.16
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (NCBI taxonomy ID 559292)
View Pfam proteome data.
Length: 417 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 23 25
Pfam Thiolase_N 36 289
disorder n/a 236 237
disorder n/a 239 250
Pfam Thiolase_C 296 416
transmembrane n/a 397 415

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P27796. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSQRLQSIKD HLVESAMGKG ESKRKNSLLE KRPEDVVIVA ANRSAIGKGF
50
51
KGAFKDVNTD YLLYNFLNEF IGRFPEPLRA DLNLIEEVAC GNVLNVGAGA
100
101
TEHRAACLAS GIPYSTPFVA LNRQCSSGLT AVNDIANKIK VGQIDIGLAL
150
151
GVESMTNNYK NVNPLGMISS EELQKNREAK KCLIPMGITN ENVAANFKIS
200
201
RKDQDEFAAN SYQKAYKAKN EGLFEDEILP IKLPDGSICQ SDEGPRPNVT
250
251
AESLSSIRPA FIKDRGTTTA GNASQVSDGV AGVLLARRSV ANQLNLPVLG
300
301
RYIDFQTVGV PPEIMGVGPA YAIPKVLEAT GLQVQDIDIF EINEAFAAQA
350
351
LYCIHKLGID LNKVNPRGGA IALGHPLGCT GARQVATILR ELKKDQIGVV
400
401
SMCIGTGMGA AAIFIKE                                    
417
 

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Checksums:
CRC64:B22AA06130829DE5
MD5:9cc3bf718a79c846d252e7b528b93f5d

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Thiolase_C 296 - 416 1AFW A 296 - 416 Jmol OpenAstexViewer
B 296 - 416 Jmol OpenAstexViewer
1PXT A 296 - 416 Jmol OpenAstexViewer
B 296 - 416 Jmol OpenAstexViewer
Thiolase_N 36 - 289 1AFW A 36 - 289 Jmol OpenAstexViewer
B 36 - 289 Jmol OpenAstexViewer
1PXT A 36 - 289 Jmol OpenAstexViewer
B 36 - 289 Jmol OpenAstexViewer