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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: ACEA_EMENI (P28298)

Summary

This is the summary of UniProt entry ACEA_EMENI (P28298).

Description: Isocitrate lyase {ECO:0000303|PubMed:1531185}
Source organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (NCBI taxonomy ID 227321)
Length: 538 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam ICL 14 536
low_complexity n/a 100 113
disorder n/a 102 103
disorder n/a 105 119
disorder n/a 141 154
disorder n/a 197 202
disorder n/a 277 278

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P28298. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSYIEEEDQR YWDEVAAVKN WWKDSRWRYT KRPFTAEQIV AKRGNLKIEY
50
51
PSNVQAKKLW GILERNFKNK EASFTYGCLD PTMVTQMAKY LDTVYVSGWQ
100
101
SSSTASSTDE PSPDLADYPM NTVPNKVNHL WMAQLFHDRK QREERMTTPK
150
151
DQRHKVANVD YLRPIIADAD TGHGGLTAVM KLTKLFVERG AAGIHIEDQA
200
201
PGTKKCGHMA GKVLVPISEH INRLVAIRAQ ADIMGTDLLA IARTDSEAAT
250
251
LITSTIDHRD HPFIIGSTNP DIQPLNDLMV MAEQAGKNGA ELQAIEDEWL
300
301
AKAGLKLFND AVVDAINNSP LPNKKAAIEK YLTQSKGKSN LEARAIAKEI
350
351
AGTDIYFDWE APRTREGYYR YQGGTQCAIN RAVAYAPFAD LIWMESKLPD
400
401
YKQAKEFADG VHAVWPEQKL AYNLSPSFNW KKAMPRDEQE TYIKRLGALG
450
451
YAWQFITLAG LHTTALISDT FAKAYAKQGM RAYGELVQEP EMANGVDVVT
500
501
HQKWSGANYV DNMLKMITGG VSSTAAMGKG VTEDQFKS             
538
 

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Checksums:
CRC64:21B5B56E5345681E
MD5:467b916658fdcc2b8614cd4ad0412900

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
ICL 14 - 520 1DQU A 14 - 520 Jmol OpenAstexViewer