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4  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: NDUS1_HUMAN (P28331)

Summary

This is the summary of UniProt entry NDUS1_HUMAN (P28331).

Description: NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial EC=1.6.5.3 EC=1.6.99.3
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 727 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam Fer2_4 29 107
Pfam NADH-G_4Fe-4S_3 113 152
Pfam Molybdopterin 301 629
disorder n/a 601 603
disorder n/a 607 610
Pfam NADH_dhqG_C 658 710

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P28331. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MLRIPVRKAL VGLSKSPKGC VRTTATAASN LIEVFVDGQS VMVEPGTTVL
50
51
QACEKVGMQI PRFCYHERLS VAGNCRMCLV EIEKAPKVVA ACAMPVMKGW
100
101
NILTNSEKSK KAREGVMEFL LANHPLDCPI CDQGGECDLQ DQSMMFGNDR
150
151
SRFLEGKRAV EDKNIGPLVK TIMTRCIQCT RCIRFASEIA GVDDLGTTGR
200
201
GNDMQVGTYI EKMFMSELSG NIIDICPVGA LTSKPYAFTA RPWETRKTES
250
251
IDVMDAVGSN IVVSTRTGEV MRILPRMHED INEEWISDKT RFAYDGLKRQ
300
301
RLTEPMVRNE KGLLTYTSWE DALSRVAGML QSFQGKDVAA IAGGLVDAEA
350
351
LVALKDLLNR VDSDTLCTEE VFPTAGAGTD LRSNYLLNTT IAGVEEADVV
400
401
LLVGTNPRFE APLFNARIRK SWLHNDLKVA LIGSPVDLTY TYDHLGDSPK
450
451
ILQDIASGSH PFSQVLKEAK KPMVVLGSSA LQRNDGAAIL AAVSSIAQKI
500
501
RMTSGVTGDW KVMNILHRIA SQVAALDLGY KPGVEAIRKN PPKVLFLLGA
550
551
DGGCITRQDL PKDCFIIYQG HHGDVGAPIA DVILPGAAYT EKSATYVNTE
600
601
GRAQQTKVAV TPPGLAREDW KIIRALSEIA GMTLPYDTLD QVRNRLEEVS
650
651
PNLVRYDDIE GANYFQQANE LSKLVNQQLL ADPLVPPQLT IKDFYMTDSI
700
701
SRASQTMAKC VKAVTEGAQA VEEPSIC                         
727
 

Show the unformatted sequence.

Checksums:
CRC64:9C35F4B8294771FB
MD5:c395ffaeb9298258b2c576d5e64684cb

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Fer2_4 30 - 107 5XTB M 30 - 107 Jmol OpenAstexViewer
5XTD M 30 - 107 Jmol OpenAstexViewer
5XTH M 30 - 107 Jmol OpenAstexViewer
5XTI BM 30 - 107 Jmol OpenAstexViewer
M 30 - 107 Jmol OpenAstexViewer
Molybdopterin 301 - 629 5XTB M 301 - 629 Jmol OpenAstexViewer
5XTD M 301 - 629 Jmol OpenAstexViewer
5XTH M 301 - 629 Jmol OpenAstexViewer
5XTI BM 301 - 629 Jmol OpenAstexViewer
M 301 - 629 Jmol OpenAstexViewer
NADH-G_4Fe-4S_3 113 - 152 5XTB M 113 - 152 Jmol OpenAstexViewer
5XTD M 113 - 152 Jmol OpenAstexViewer
5XTH M 113 - 152 Jmol OpenAstexViewer
5XTI BM 113 - 152 Jmol OpenAstexViewer
M 113 - 152 Jmol OpenAstexViewer
NADH_dhqG_C 658 - 710 5XTB M 658 - 710 Jmol OpenAstexViewer
5XTD M 658 - 710 Jmol OpenAstexViewer
5XTH M 658 - 710 Jmol OpenAstexViewer
5XTI BM 658 - 710 Jmol OpenAstexViewer
M 658 - 710 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.