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6  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RXRB_HUMAN (P28702)

Summary

This is the summary of UniProt entry RXRB_HUMAN (P28702).

Description: Retinoic acid receptor RXR-beta
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 533 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 195
low_complexity n/a 45 53
low_complexity n/a 53 68
low_complexity n/a 68 87
low_complexity n/a 85 133
low_complexity n/a 136 159
low_complexity n/a 191 198
disorder n/a 202 205
Pfam zf-C4 203 272
low_complexity n/a 250 264
disorder n/a 273 299
low_complexity n/a 281 297
disorder n/a 303 307
disorder n/a 312 336
low_complexity n/a 320 331
Pfam Hormone_recep 331 513

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P28702. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSWAARPPFL PQRHAAGQCG PVGVRKEMHC GVASRWRRRR PWLDPAAAAA
50
51
AAVAGGEQQT PEPEPGEAGR DGMGDSGRDS RSPDSSSPNP LPQGVPPPSP
100
101
PGPPLPPSTA PSLGGSGAPP PPPMPPPPLG SPFPVISSSM GSPGLPPPAP
150
151
PGFSGPVSSP QINSTVSLPG GGSGPPEDVK PPVLGVRGLH CPPPPGGPGA
200
201
GKRLCAICGD RSSGKHYGVY SCEGCKGFFK RTIRKDLTYS CRDNKDCTVD
250
251
KRQRNRCQYC RYQKCLATGM KREAVQEERQ RGKDKDGDGE GAGGAPEEMP
300
301
VDRILEAELA VEQKSDQGVE GPGGTGGSGS SPNDPVTNIC QAADKQLFTL
350
351
VEWAKRIPHF SSLPLDDQVI LLRAGWNELL IASFSHRSID VRDGILLATG
400
401
LHVHRNSAHS AGVGAIFDRV LTELVSKMRD MRMDKTELGC LRAIILFNPD
450
451
AKGLSNPSEV EVLREKVYAS LETYCKQKYP EQQGRFAKLL LRLPALRSIG
500
501
LKCLEHLFFF KLIGDTPIDT FLMEMLEAPH QLA                  
533
 

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Checksums:
CRC64:D0069FE93AC16A04
MD5:109711b8919231164905406c5c948b68

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Hormone_recep 331 - 513 1UHL A 331 - 513 Jmol OpenAstexViewer
334 - 513 5KYJ B 334 - 513 Jmol OpenAstexViewer
F 334 - 513 Jmol OpenAstexViewer
335 - 513 1H9U A 335 - 513 Jmol OpenAstexViewer
B 335 - 513 Jmol OpenAstexViewer
C 335 - 513 Jmol OpenAstexViewer
D 335 - 513 Jmol OpenAstexViewer
5HJP C 335 - 513 Jmol OpenAstexViewer
5I4V B 335 - 513 Jmol OpenAstexViewer
F 335 - 513 Jmol OpenAstexViewer
5KYA B 335 - 513 Jmol OpenAstexViewer
F 335 - 513 Jmol OpenAstexViewer
336 - 513 5HJP A 336 - 513 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.