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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: IDH1_YEAST (P28834)

Summary

This is the summary of UniProt entry IDH1_YEAST (P28834).

Description: Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial EC=1.1.1.41
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (NCBI taxonomy ID 559292)
View Pfam proteome data.
Length: 360 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam Iso_dh 30 357
low_complexity n/a 250 270
disorder n/a 333 345

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P28834. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MLNRTIAKRT LATAAQAERT LPKKYGGRFT VTLIPGDGVG KEITDSVRTI
50
51
FEAENIPIDW ETINIKQTDH KEGVYEAVES LKRNKIGLKG LWHTPADQTG
100
101
HGSLNVALRK QLDIYANVAL FKSLKGVKTR IPDIDLIVIR ENTEGEFSGL
150
151
EHESVPGVVE SLKVMTRPKT ERIARFAFDF AKKYNRKSVT AVHKANIMKL
200
201
GDGLFRNIIT EIGQKEYPDI DVSSIIVDNA SMQAVAKPHQ FDVLVTPSMY
250
251
GTILGNIGAA LIGGPGLVAG ANFGRDYAVF EPGSRHVGLD IKGQNVANPT
300
301
AMILSSTLML NHLGLNEYAT RISKAVHETI AEGKHTTRDI GGSSSTTDFT
350
351
NEIINKLSTM                                            
360
 

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Checksums:
CRC64:0932E7B3CD685240
MD5:b7ef3de09ec5cb1b11472e9c07171923

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Iso_dh 30 - 357 3BLV A 19 - 346 Jmol OpenAstexViewer
C 19 - 346 Jmol OpenAstexViewer
E 19 - 346 Jmol OpenAstexViewer
G 19 - 346 Jmol OpenAstexViewer
3BLW A 19 - 346 Jmol OpenAstexViewer
C 19 - 346 Jmol OpenAstexViewer
E 19 - 346 Jmol OpenAstexViewer
G 19 - 346 Jmol OpenAstexViewer
I 19 - 346 Jmol OpenAstexViewer
K 19 - 346 Jmol OpenAstexViewer
M 19 - 346 Jmol OpenAstexViewer
O 19 - 346 Jmol OpenAstexViewer
3BLX A 19 - 346 Jmol OpenAstexViewer
C 19 - 346 Jmol OpenAstexViewer
E 19 - 346 Jmol OpenAstexViewer
G 19 - 346 Jmol OpenAstexViewer
I 19 - 346 Jmol OpenAstexViewer
K 19 - 346 Jmol OpenAstexViewer
M 19 - 346 Jmol OpenAstexViewer
O 19 - 346 Jmol OpenAstexViewer