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6  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: 3MG_HUMAN (P29372)

Summary

This is the summary of UniProt entry 3MG_HUMAN (P29372).

Description: DNA-3-methyladenine glycosylase EC=3.2.2.21
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 298 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 3
disorder n/a 6 64
disorder n/a 67 69
disorder n/a 72 74
Pfam Pur_DNA_glyco 89 283
disorder n/a 119 125
disorder n/a 128 147
low_complexity n/a 254 267

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P29372. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MVTPALQMKK PKQFCRRMGQ KKQRPARAGQ PHSSSDAAQA PAEQPHSSSD
50
51
AAQAPCPRER CLGPPTTPGP YRSIYFSSPK GHLTRLGLEF FDQPAVPLAR
100
101
AFLGQVLVRR LPNGTELRGR IVETEAYLGP EDEAAHSRGG RQTPRNRGMF
150
151
MKPGTLYVYI IYGMYFCMNI SSQGDGACVL LRALEPLEGL ETMRQLRSTL
200
201
RKGTASRVLK DRELCSGPSK LCQALAINKS FDQRDLAQDE AVWLERGPLE
250
251
PSEPAVVAAA RVGVGHAGEW ARKPLRFYVR GSPWVSVVDR VAEQDTQA  
298
 

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Checksums:
CRC64:BEA8C4CB250D572B
MD5:fe0baeee7628a5cfa0bdd4a3d9747aed

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Pur_DNA_glyco 89 - 283 1BNK A 89 - 283 Jmol OpenAstexViewer
1EWN A 89 - 283 Jmol OpenAstexViewer
1F4R A 89 - 283 Jmol OpenAstexViewer
1F6O A 89 - 283 Jmol OpenAstexViewer
3QI5 A 89 - 283 Jmol OpenAstexViewer
B 89 - 283 Jmol OpenAstexViewer
3UBY A 89 - 283 Jmol OpenAstexViewer
B 89 - 283 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.