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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PRDX3_HUMAN (P30048)

Summary

This is the summary of UniProt entry PRDX3_HUMAN (P30048).

Description: Thioredoxin-dependent peroxide reductase, mitochondrial
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 256 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam AhpC-TSA 65 198
Pfam 1-cysPrx_C 218 253
disorder n/a 232 239
disorder n/a 244 246

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P30048. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAAAVGRLLR ASVARHVSAI PWGISATAAL RPAACGRTSL TNLLCSGSSQ
50
51
AKLFSTSSSC HAPAVTQHAP YFKGTAVVNG EFKDLSLDDF KGKYLVLFFY
100
101
PLDFTFVCPT EIVAFSDKAN EFHDVNCEVV AVSVDSHFSH LAWINTPRKN
150
151
GGLGHMNIAL LSDLTKQISR DYGVLLEGSG LALRGLFIID PNGVIKHLSV
200
201
NDLPVGRSVE ETLRLVKAFQ YVETHGEVCP ANWTPDSPTI KPSPAASKEY
250
251
FQKVNQ                                                
256
 

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Checksums:
CRC64:8BEB7F5E55BFE9BE
MD5:467c6c00188b93de32c9a369f7be138e

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
1-cysPrx_C 218 - 253 5JCG A 157 - 192 Jmol OpenAstexViewer
B 157 - 192 Jmol OpenAstexViewer
C 157 - 192 Jmol OpenAstexViewer
D 157 - 192 Jmol OpenAstexViewer
E 157 - 192 Jmol OpenAstexViewer
F 157 - 192 Jmol OpenAstexViewer
G 157 - 192 Jmol OpenAstexViewer
H 157 - 192 Jmol OpenAstexViewer
I 157 - 192 Jmol OpenAstexViewer
5UCX A 157 - 192 Jmol OpenAstexViewer
B 157 - 192 Jmol OpenAstexViewer
C 157 - 192 Jmol OpenAstexViewer
D 157 - 192 Jmol OpenAstexViewer
E 157 - 192 Jmol OpenAstexViewer
F 157 - 192 Jmol OpenAstexViewer
G 157 - 192 Jmol OpenAstexViewer
H 157 - 192 Jmol OpenAstexViewer
I 157 - 192 Jmol OpenAstexViewer
AhpC-TSA 65 - 198 5JCG A 4 - 137 Jmol OpenAstexViewer
B 4 - 137 Jmol OpenAstexViewer
C 4 - 137 Jmol OpenAstexViewer
D 4 - 137 Jmol OpenAstexViewer
E 4 - 137 Jmol OpenAstexViewer
F 4 - 137 Jmol OpenAstexViewer
G 4 - 137 Jmol OpenAstexViewer
H 4 - 137 Jmol OpenAstexViewer
I 4 - 137 Jmol OpenAstexViewer
5UCX A 4 - 137 Jmol OpenAstexViewer
B 4 - 137 Jmol OpenAstexViewer
C 4 - 137 Jmol OpenAstexViewer
D 4 - 137 Jmol OpenAstexViewer
E 4 - 137 Jmol OpenAstexViewer
F 4 - 137 Jmol OpenAstexViewer
G 4 - 137 Jmol OpenAstexViewer
H 4 - 137 Jmol OpenAstexViewer
I 4 - 137 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.