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4  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MPIP3_HUMAN (P30307)

Summary

This is the summary of UniProt entry MPIP3_HUMAN (P30307).

Description: M-phase inducer phosphatase 3 EC=3.1.3.48
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 473 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 27
low_complexity n/a 5 22
disorder n/a 83 115
disorder n/a 121 122
disorder n/a 129 133
disorder n/a 137 164
disorder n/a 169 195
Pfam M-inducer_phosp 191 271
disorder n/a 207 230
disorder n/a 232 233
Pfam Rhodanese 308 422

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P30307. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSTELFSSTR EEGSSGSGPS FRSNQRKMLN LLLERDTSFT VCPDVPRTPV
50
51
GKFLGDSANL SILSGGTPKR CLDLSNLSSG EITATQLTTS ADLDETGHLD
100
101
SSGLQEVHLA GMNHDQHLMK CSPAQLLCST PNGLDRGHRK RDAMCSSSAN
150
151
KENDNGNLVD SEMKYLGSPI TTVPKLDKNP NLGEDQAEEI SDELMEFSLK
200
201
DQEAKVSRSG LYRSPSMPEN LNRPRLKQVE KFKDNTIPDK VKKKYFSGQG
250
251
KLRKGLCLKK TVSLCDITIT QMLEEDSNQG HLIGDFSKVC ALPTVSGKHQ
300
301
DLKYVNPETV AALLSGKFQG LIEKFYVIDC RYPYEYLGGH IQGALNLYSQ
350
351
EELFNFFLKK PIVPLDTQKR IIIVFHCEFS SERGPRMCRC LREEDRSLNQ
400
401
YPALYYPELY ILKGGYRDFF PEYMELCEPQ SYCPMHHQDH KTELLRCRSQ
450
451
SKVQEGERQL REQIALLVKD MSP                             
473
 

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Checksums:
CRC64:0658A1F1B9B8996A
MD5:004cef7b0dae937e6d722817c17ed889

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
M-inducer_phosp 207 - 223 5M37 D 207 - 223 Jmol OpenAstexViewer
207 - 224 5M37 C 207 - 224 Jmol OpenAstexViewer
207 - 225 5M36 C 207 - 225 Jmol OpenAstexViewer
211 - 220 5M35 C 211 - 220 Jmol OpenAstexViewer
212 - 220 5M36 D 212 - 220 Jmol OpenAstexViewer
213 - 219 5M35 D 213 - 219 Jmol OpenAstexViewer
Rhodanese 308 - 422 3OP3 A 308 - 422 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.