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65  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ACRB_ECOLI (P31224)

Summary

This is the summary of UniProt entry ACRB_ECOLI (P31224).

Description: Multidrug efflux pump subunit AcrB
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
View Pfam proteome data.
Length: 1049 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam ACR_tran 1 1030
transmembrane n/a 12 32
low_complexity n/a 14 27
low_complexity n/a 292 304
transmembrane n/a 340 359
transmembrane n/a 366 390
transmembrane n/a 396 416
transmembrane n/a 437 458
transmembrane n/a 470 493
transmembrane n/a 541 557
disorder n/a 714 717
disorder n/a 724 727
transmembrane n/a 875 892
transmembrane n/a 899 919
transmembrane n/a 925 946
transmembrane n/a 975 995
low_complexity n/a 1001 1015
transmembrane n/a 1007 1029
low_complexity n/a 1019 1032
disorder n/a 1040 1042
disorder n/a 1044 1049

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P31224. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPNFFIDRPI FAWVIAIIIM LAGGLAILKL PVAQYPTIAP PAVTISASYP
50
51
GADAKTVQDT VTQVIEQNMN GIDNLMYMSS NSDSTGTVQI TLTFESGTDA
100
101
DIAQVQVQNK LQLAMPLLPQ EVQQQGVSVE KSSSSFLMVV GVINTDGTMT
150
151
QEDISDYVAA NMKDAISRTS GVGDVQLFGS QYAMRIWMNP NELNKFQLTP
200
201
VDVITAIKAQ NAQVAAGQLG GTPPVKGQQL NASIIAQTRL TSTEEFGKIL
250
251
LKVNQDGSRV LLRDVAKIEL GGENYDIIAE FNGQPASGLG IKLATGANAL
300
301
DTAAAIRAEL AKMEPFFPSG LKIVYPYDTT PFVKISIHEV VKTLVEAIIL
350
351
VFLVMYLFLQ NFRATLIPTI AVPVVLLGTF AVLAAFGFSI NTLTMFGMVL
400
401
AIGLLVDDAI VVVENVERVM AEEGLPPKEA TRKSMGQIQG ALVGIAMVLS
450
451
AVFVPMAFFG GSTGAIYRQF SITIVSAMAL SVLVALILTP ALCATMLKPI
500
501
AKGDHGEGKK GFFGWFNRMF EKSTHHYTDS VGGILRSTGR YLVLYLIIVV
550
551
GMAYLFVRLP SSFLPDEDQG VFMTMVQLPA GATQERTQKV LNEVTHYYLT
600
601
KEKNNVESVF AVNGFGFAGR GQNTGIAFVS LKDWADRPGE ENKVEAITMR
650
651
ATRAFSQIKD AMVFAFNLPA IVELGTATGF DFELIDQAGL GHEKLTQARN
700
701
QLLAEAAKHP DMLTSVRPNG LEDTPQFKID IDQEKAQALG VSINDINTTL
750
751
GAAWGGSYVN DFIDRGRVKK VYVMSEAKYR MLPDDIGDWY VRAADGQMVP
800
801
FSAFSSSRWE YGSPRLERYN GLPSMEILGQ AAPGKSTGEA MELMEQLASK
850
851
LPTGVGYDWT GMSYQERLSG NQAPSLYAIS LIVVFLCLAA LYESWSIPFS
900
901
VMLVVPLGVI GALLAATFRG LTNDVYFQVG LLTTIGLSAK NAILIVEFAK
950
951
DLMDKEGKGL IEATLDAVRM RLRPILMTSL AFILGVMPLV ISTGAGSGAQ
1000
1001
NAVGTGVMGG MVTATVLAIF FVPVFFVVVR RRFSRKNEDI EHSHTVDHH 
1049
 

Show the unformatted sequence.

Checksums:
CRC64:19670E3C4CC29055
MD5:c564a138f040b7ce63fb3db8488183e1

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
ACR_tran 1 - 1030 2DHH A 1 - 1030 Jmol OpenAstexViewer
B 1 - 1030 Jmol OpenAstexViewer
C 1 - 1030 Jmol OpenAstexViewer
2DR6 A 1 - 1030 Jmol OpenAstexViewer
B 1 - 1030 Jmol OpenAstexViewer
C 1 - 1030 Jmol OpenAstexViewer
2DRD A 1 - 1030 Jmol OpenAstexViewer
B 1 - 1030 Jmol OpenAstexViewer
C 1 - 1030 Jmol OpenAstexViewer
2I6W A 1 - 1030 Jmol OpenAstexViewer
2J8S A 1 - 1030 Jmol OpenAstexViewer
B 1 - 1030 Jmol OpenAstexViewer
C 1 - 1030 Jmol OpenAstexViewer
2RDD A 1 - 1030 Jmol OpenAstexViewer
3AOA A 1 - 1030 Jmol OpenAstexViewer
B 1 - 1030 Jmol OpenAstexViewer
C 1 - 1030 Jmol OpenAstexViewer
3AOB A 1 - 1030 Jmol OpenAstexViewer
B 1 - 1030 Jmol OpenAstexViewer
C 1 - 1030 Jmol OpenAstexViewer
3AOC A 1 - 1030 Jmol OpenAstexViewer
B 1 - 1030 Jmol OpenAstexViewer
C 1 - 1030 Jmol OpenAstexViewer
3AOD A 1 - 1030 Jmol OpenAstexViewer
B 1 - 1030 Jmol OpenAstexViewer
C 1 - 1030 Jmol OpenAstexViewer
3D9B A 1 - 1030 Jmol OpenAstexViewer
3NOC A 1 - 1030 Jmol OpenAstexViewer
B 1 - 1030 Jmol OpenAstexViewer
C 1 - 1030 Jmol OpenAstexViewer
3NOG A 1 - 1030 Jmol OpenAstexViewer
B 1 - 1030 Jmol OpenAstexViewer
C 1 - 1030 Jmol OpenAstexViewer
3W9H A 1 - 1030 Jmol OpenAstexViewer
B 1 - 1030 Jmol OpenAstexViewer
C 1 - 1030 Jmol OpenAstexViewer
4C48 A 1 - 1030 Jmol OpenAstexViewer
4CDI A 1 - 1030 Jmol OpenAstexViewer
4DX5 A 1 - 1030 Jmol OpenAstexViewer
B 1 - 1030 Jmol OpenAstexViewer
C 1 - 1030 Jmol OpenAstexViewer
4DX6 A 1 - 1030 Jmol OpenAstexViewer
B 1 - 1030 Jmol OpenAstexViewer
C 1 - 1030 Jmol OpenAstexViewer
4DX7 A 1 - 1030 Jmol OpenAstexViewer
B 1 - 1030 Jmol OpenAstexViewer
C 1 - 1030 Jmol OpenAstexViewer
4U8V A 1 - 1030 Jmol OpenAstexViewer
B 1 - 1030 Jmol OpenAstexViewer
C 1 - 1030 Jmol OpenAstexViewer
4U8Y A 1 - 1030 Jmol OpenAstexViewer
B 1 - 1030 Jmol OpenAstexViewer
C 1 - 1030 Jmol OpenAstexViewer
4U95 A 1 - 1030 Jmol OpenAstexViewer
B 1 - 1030 Jmol OpenAstexViewer
C 1 - 1030 Jmol OpenAstexViewer
4U96 A 1 - 1030 Jmol OpenAstexViewer
B 1 - 1030 Jmol OpenAstexViewer
C 1 - 1030 Jmol OpenAstexViewer
4ZLJ A 1 - 1030 Jmol OpenAstexViewer
4ZLL A 1 - 1030 Jmol OpenAstexViewer
4ZLN A 1 - 1025 Jmol OpenAstexViewer
5JMN A 1 - 1030 Jmol OpenAstexViewer
B 1 - 1030 Jmol OpenAstexViewer
C 1 - 1030 Jmol OpenAstexViewer
5NC5 A 1 - 1030 Jmol OpenAstexViewer
B 1 - 1030 Jmol OpenAstexViewer
C 1 - 1030 Jmol OpenAstexViewer
5NG5 J 1 - 1030 Jmol OpenAstexViewer
K 1 - 1030 Jmol OpenAstexViewer
L 1 - 1030 Jmol OpenAstexViewer
5O66 J 1 - 1030 Jmol OpenAstexViewer
K 1 - 1030 Jmol OpenAstexViewer
L 1 - 1030 Jmol OpenAstexViewer
5V5S J 1 - 1030 Jmol OpenAstexViewer
K 1 - 1030 Jmol OpenAstexViewer
L 1 - 1030 Jmol OpenAstexViewer
5YIL A 1 - 1027 Jmol OpenAstexViewer
B 1 - 1027 Jmol OpenAstexViewer
C 1 - 1027 Jmol OpenAstexViewer
2 - 1030 2GIF A 2 - 1030 Jmol OpenAstexViewer
B 2 - 1030 Jmol OpenAstexViewer
C 2 - 1030 Jmol OpenAstexViewer
2HRT A 2 - 1030 Jmol OpenAstexViewer
B 2 - 1030 Jmol OpenAstexViewer
C 2 - 1030 Jmol OpenAstexViewer
D 2 - 1030 Jmol OpenAstexViewer
E 2 - 1030 Jmol OpenAstexViewer
F 2 - 1030 Jmol OpenAstexViewer
2W1B A 2 - 1030 Jmol OpenAstexViewer
4ZIT A 2 - 1030 Jmol OpenAstexViewer
B 2 - 1030 Jmol OpenAstexViewer
C 2 - 1030 Jmol OpenAstexViewer
D 2 - 1030 Jmol OpenAstexViewer
E 2 - 1030 Jmol OpenAstexViewer
F 2 - 1030 Jmol OpenAstexViewer
4ZIV A 2 - 1030 Jmol OpenAstexViewer
B 2 - 1030 Jmol OpenAstexViewer
C 2 - 1030 Jmol OpenAstexViewer
D 2 - 1030 Jmol OpenAstexViewer
E 2 - 1030 Jmol OpenAstexViewer
F 2 - 1030 Jmol OpenAstexViewer
4ZIW A 2 - 1025 Jmol OpenAstexViewer
B 2 - 1025 Jmol OpenAstexViewer
C 2 - 1025 Jmol OpenAstexViewer
D 2 - 1025 Jmol OpenAstexViewer
E 2 - 1025 Jmol OpenAstexViewer
F 2 - 1025 Jmol OpenAstexViewer
4ZJL A 2 - 1030 Jmol OpenAstexViewer
B 2 - 1030 Jmol OpenAstexViewer
C 2 - 1030 Jmol OpenAstexViewer
D 2 - 1030 Jmol OpenAstexViewer
E 2 - 1030 Jmol OpenAstexViewer
F 2 - 1030 Jmol OpenAstexViewer
4ZJO A 2 - 1030 Jmol OpenAstexViewer
B 2 - 1030 Jmol OpenAstexViewer
C 2 - 1030 Jmol OpenAstexViewer
D 2 - 1030 Jmol OpenAstexViewer
E 2 - 1030 Jmol OpenAstexViewer
F 2 - 1030 Jmol OpenAstexViewer
4ZJQ A 2 - 1025 Jmol OpenAstexViewer
B 2 - 1025 Jmol OpenAstexViewer
C 2 - 1025 Jmol OpenAstexViewer
D 2 - 1025 Jmol OpenAstexViewer
E 2 - 1025 Jmol OpenAstexViewer
F 2 - 1025 Jmol OpenAstexViewer
39 - 864 5EN5 A 39 - 864 Jmol OpenAstexViewer
B 39 - 864 Jmol OpenAstexViewer
C 39 - 864 Jmol OpenAstexViewer
5ENO B 39 - 864 Jmol OpenAstexViewer
C 39 - 864 Jmol OpenAstexViewer
5ENP B 39 - 864 Jmol OpenAstexViewer
C 39 - 864 Jmol OpenAstexViewer
5ENQ B 39 - 864 Jmol OpenAstexViewer
C 39 - 864 Jmol OpenAstexViewer
5ENR B 39 - 864 Jmol OpenAstexViewer
C 39 - 864 Jmol OpenAstexViewer
5ENS B 39 - 864 Jmol OpenAstexViewer
C 39 - 864 Jmol OpenAstexViewer
5ENT A 39 - 864 Jmol OpenAstexViewer
C 39 - 864 Jmol OpenAstexViewer
39 - 865 5ENO A 39 - 865 Jmol OpenAstexViewer
5ENP A 39 - 865 Jmol OpenAstexViewer
5ENQ A 39 - 865 Jmol OpenAstexViewer
5ENR A 39 - 865 Jmol OpenAstexViewer
5ENS A 39 - 865 Jmol OpenAstexViewer
5ENT B 39 - 865 Jmol OpenAstexViewer
7 - 1030 1IWG A 7 - 1030 Jmol OpenAstexViewer
1OY6 A 7 - 1030 Jmol OpenAstexViewer
1OY8 A 7 - 1030 Jmol OpenAstexViewer
1OY9 A 7 - 1030 Jmol OpenAstexViewer
1OYD A 7 - 1030 Jmol OpenAstexViewer
1OYE A 7 - 1030 Jmol OpenAstexViewer
1T9T A 7 - 1030 Jmol OpenAstexViewer
1T9U A 7 - 1030 Jmol OpenAstexViewer
1T9V A 7 - 1030 Jmol OpenAstexViewer
1T9W A 7 - 1030 Jmol OpenAstexViewer
1T9X A 7 - 1030 Jmol OpenAstexViewer
1T9Y A 7 - 1030 Jmol OpenAstexViewer
2HQC A 7 - 1030 Jmol OpenAstexViewer
2HQD A 7 - 1030 Jmol OpenAstexViewer
2HQF A 7 - 1030 Jmol OpenAstexViewer
2HQG A 7 - 1030 Jmol OpenAstexViewer
4K7Q A 7 - 1030 Jmol OpenAstexViewer