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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: HXA13_HUMAN (P31271)

Summary

This is the summary of UniProt entry HXA13_HUMAN (P31271).

Description: Homeobox protein Hox-A13
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 388 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
low_complexity n/a 36 83
low_complexity n/a 93 149
disorder n/a 103 104
disorder n/a 137 146
Pfam HoxA13_N 138 224
low_complexity n/a 148 167
low_complexity n/a 194 206
disorder n/a 251 273
disorder n/a 287 288
disorder n/a 296 297
disorder n/a 301 307
disorder n/a 312 325
Pfam Homeodomain 323 379
disorder n/a 328 330
disorder n/a 348 349
disorder n/a 352 358
disorder n/a 380 388

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P31271. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTASVLLHPR WIEPTVMFLY DNGGGLVADE LNKNMEGAAA AAAAAAAAAA
50
51
AGAGGGGFPH PAAAAAGGNF SVAAAAAAAA AAAANQCRNL MAHPAPLAPG
100
101
AASAYSSAPG EAPPSAAAAA AAAAAAAAAA AAASSSGGPG PAGPAGAEAA
150
151
KQCSPCSAAA QSSSGPAALP YGYFGSGYYP CARMGPHPNA IKSCAQPASA
200
201
AAAAAFADKY MDTAGPAAEE FSSRAKEFAF YHQGYAAGPY HHHQPMPGYL
250
251
DMPVVPGLGG PGESRHEPLG LPMESYQPWA LPNGWNGQMY CPKEQAQPPH
300
301
LWKSTLPDVV SHPSDASSYR RGRKKRVPYT KVQLKELERE YATNKFITKD
350
351
KRRRISATTN LSERQVTIWF QNRRVKEKKV INKLKTTS             
388
 

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Checksums:
CRC64:3512E7622FA931C4
MD5:f67a8ccd487e4f2241dc47946ff1e47b

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Homeodomain 323 - 379 2L7Z A 8 - 64 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.