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5  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CASQ1_HUMAN (P31415)

Summary

This is the summary of UniProt entry CASQ1_HUMAN (P31415).

Description: Calsequestrin-1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 396 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 34
disorder n/a 2 3
low_complexity n/a 8 25
Pfam Calsequestrin 11 396
disorder n/a 36 37
disorder n/a 246 249
disorder n/a 251 253
disorder n/a 300 304
disorder n/a 353 355
disorder n/a 357 396
low_complexity n/a 370 383
low_complexity n/a 388 395

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P31415. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSATDRMGPR AVPGLRLALL LLLVLGTPKS GVQGQEGLDF PEYDGVDRVI
50
51
NVNAKNYKNV FKKYEVLALL YHEPPEDDKA SQRQFEMEEL ILELAAQVLE
100
101
DKGVGFGLVD SEKDAAVAKK LGLTEVDSMY VFKGDEVIEY DGEFSADTIV
150
151
EFLLDVLEDP VELIEGEREL QAFENIEDEI KLIGYFKSKD SEHYKAFEDA
200
201
AEEFHPYIPF FATFDSKVAK KLTLKLNEID FYEAFMEEPV TIPDKPNSEE
250
251
EIVNFVEEHR RSTLRKLKPE SMYETWEDDM DGIHIVAFAE EADPDGFEFL
300
301
ETLKAVAQDN TENPDLSIIW IDPDDFPLLV PYWEKTFDID LSAPQIGVVN
350
351
VTDADSVWME MDDEEDLPSA EELEDWLEDV LEGEINTEDD DDDDDD    
396
 

Show the unformatted sequence.

Checksums:
CRC64:C20388AD8870E12D
MD5:cee36e0f28432096402713d2b688edad

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Calsequestrin 35 - 387 5CRH B 1 - 353 Jmol OpenAstexViewer
35 - 388 5CRG A 1 - 354 Jmol OpenAstexViewer
B 1 - 354 Jmol OpenAstexViewer
C 1 - 354 Jmol OpenAstexViewer
D 1 - 354 Jmol OpenAstexViewer
5CRH A 1 - 354 Jmol OpenAstexViewer
36 - 383 5CRD A 2 - 349 Jmol OpenAstexViewer
37 - 383 5CRE A 3 - 349 Jmol OpenAstexViewer
37 - 388 3UOM A 3 - 354 Jmol OpenAstexViewer
38 - 388 3UOM C 4 - 354 Jmol OpenAstexViewer
E 4 - 354 Jmol OpenAstexViewer
39 - 388 3UOM B 5 - 354 Jmol OpenAstexViewer
D 5 - 354 Jmol OpenAstexViewer
F 5 - 354 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.