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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: OTX1_HUMAN (P32242)

Summary

This is the summary of UniProt entry OTX1_HUMAN (P32242).

Description: Homeobox protein OTX1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 354 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 16 17
disorder n/a 26 45
Pfam Homeodomain 39 95
disorder n/a 86 156
low_complexity n/a 116 124
low_complexity n/a 128 164
low_complexity n/a 162 174
disorder n/a 163 164
low_complexity n/a 168 200
disorder n/a 176 181
Pfam TF_Otx 178 279
disorder n/a 183 209
low_complexity n/a 210 218
low_complexity n/a 219 241
disorder n/a 259 304
low_complexity n/a 274 284
low_complexity n/a 282 307

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P32242. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MMSYLKQPPY GMNGLGLAGP AMDLLHPSVG YPATPRKQRR ERTTFTRSQL
50
51
DVLEALFAKT RYPDIFMREE VALKINLPES RVQVWFKNRR AKCRQQQQSG
100
101
SGTKSRPAKK KSSPVRESSG SESSGQFTPP AVSSSASSSS SASSSSANPA
150
151
AAAAAGLGGN PVAAASSLST PAASSIWSPA SISPGSAPAS VSVPEPLAAP
200
201
SNTSCMQRSV AAGAATAAAS YPMSYGQGGS YGQGYPTPSS SYFGGVDCSS
250
251
YLAPMHSHHH PHQLSPMAPS SMAGHHHHHP HAHHPLSQSS GHHHHHHHHH
300
301
HQGYGGSGLA FNSADCLDYK EPGAAAASSA WKLNFNSPDC LDYKDQASWR
350
351
FQVL                                                  
354
 

Show the unformatted sequence.

Checksums:
CRC64:E32C1E47464BDDAA
MD5:4307d3db659132103a0d4e6d8434de52

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.