Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
9  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: P5CR1_HUMAN (P32322)

Summary

This is the summary of UniProt entry P5CR1_HUMAN (P32322).

Description: Pyrroline-5-carboxylate reductase 1, mitochondrial EC=1.5.1.2
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 319 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
sig_p n/a 1 26
Pfam F420_oxidored 2 98
Pfam P5CR_dimer 164 268
disorder n/a 222 233
disorder n/a 268 269
disorder n/a 273 275
disorder n/a 294 319

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P32322. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSVGFIGAGQ LAFALAKGFT AAGVLAAHKI MASSPDMDLA TVSALRKMGV
50
51
KLTPHNKETV QHSDVLFLAV KPHIIPFILD EIGADIEDRH IVVSCAAGVT
100
101
ISSIEKKLSA FRPAPRVIRC MTNTPVVVRE GATVYATGTH AQVEDGRLME
150
151
QLLSSVGFCT EVEEDLIDAV TGLSGSGPAY AFTALDALAD GGVKMGLPRR
200
201
LAVRLGAQAL LGAAKMLLHS EQHPGQLKDN VSSPGGATIH ALHVLESGGF
250
251
RSLLINAVEA SCIRTRELQS MADQEQVSPA AIKKTILDKV KLDSPAGTAL
300
301
SPSGHTKLLP RSLAPAGKD                                  
319
 

Show the unformatted sequence.

Checksums:
CRC64:9E8C4DED0638EFC5
MD5:5d7922adb193213933007db432fa9622

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
F420_oxidored 2 - 98 2GER A 2 - 98 Jmol OpenAstexViewer
B 2 - 98 Jmol OpenAstexViewer
C 2 - 98 Jmol OpenAstexViewer
D 2 - 98 Jmol OpenAstexViewer
E 2 - 98 Jmol OpenAstexViewer
2GR9 A 2 - 98 Jmol OpenAstexViewer
B 2 - 98 Jmol OpenAstexViewer
C 2 - 98 Jmol OpenAstexViewer
D 2 - 98 Jmol OpenAstexViewer
E 2 - 98 Jmol OpenAstexViewer
2GRA A 2 - 98 Jmol OpenAstexViewer
B 2 - 98 Jmol OpenAstexViewer
C 2 - 98 Jmol OpenAstexViewer
D 2 - 98 Jmol OpenAstexViewer
E 2 - 98 Jmol OpenAstexViewer
2IZZ A 2 - 98 Jmol OpenAstexViewer
B 2 - 98 Jmol OpenAstexViewer
C 2 - 98 Jmol OpenAstexViewer
D 2 - 98 Jmol OpenAstexViewer
E 2 - 98 Jmol OpenAstexViewer
5UAT A 2 - 98 Jmol OpenAstexViewer
B 2 - 98 Jmol OpenAstexViewer
C 2 - 98 Jmol OpenAstexViewer
D 2 - 98 Jmol OpenAstexViewer
E 2 - 98 Jmol OpenAstexViewer
5UAU A 2 - 98 Jmol OpenAstexViewer
B 2 - 98 Jmol OpenAstexViewer
C 2 - 98 Jmol OpenAstexViewer
D 2 - 98 Jmol OpenAstexViewer
E 2 - 98 Jmol OpenAstexViewer
5UAV A 2 - 98 Jmol OpenAstexViewer
B 2 - 98 Jmol OpenAstexViewer
C 2 - 98 Jmol OpenAstexViewer
D 2 - 98 Jmol OpenAstexViewer
E 2 - 98 Jmol OpenAstexViewer
5UAW A 2 - 98 Jmol OpenAstexViewer
B 2 - 98 Jmol OpenAstexViewer
C 2 - 98 Jmol OpenAstexViewer
D 2 - 98 Jmol OpenAstexViewer
E 2 - 98 Jmol OpenAstexViewer
5UAX A 2 - 98 Jmol OpenAstexViewer
B 2 - 98 Jmol OpenAstexViewer
C 2 - 98 Jmol OpenAstexViewer
D 2 - 98 Jmol OpenAstexViewer
E 2 - 98 Jmol OpenAstexViewer
P5CR_dimer 164 - 268 2GER A 164 - 268 Jmol OpenAstexViewer
B 164 - 268 Jmol OpenAstexViewer
C 164 - 268 Jmol OpenAstexViewer
D 164 - 268 Jmol OpenAstexViewer
E 164 - 268 Jmol OpenAstexViewer
2GR9 A 164 - 268 Jmol OpenAstexViewer
B 164 - 268 Jmol OpenAstexViewer
C 164 - 268 Jmol OpenAstexViewer
D 164 - 268 Jmol OpenAstexViewer
E 164 - 268 Jmol OpenAstexViewer
2GRA A 164 - 268 Jmol OpenAstexViewer
B 164 - 268 Jmol OpenAstexViewer
C 164 - 268 Jmol OpenAstexViewer
D 164 - 268 Jmol OpenAstexViewer
E 164 - 268 Jmol OpenAstexViewer
2IZZ A 164 - 268 Jmol OpenAstexViewer
B 164 - 268 Jmol OpenAstexViewer
C 164 - 268 Jmol OpenAstexViewer
D 164 - 268 Jmol OpenAstexViewer
E 164 - 268 Jmol OpenAstexViewer
5UAT A 164 - 268 Jmol OpenAstexViewer
B 164 - 268 Jmol OpenAstexViewer
C 164 - 268 Jmol OpenAstexViewer
D 164 - 268 Jmol OpenAstexViewer
E 164 - 268 Jmol OpenAstexViewer
5UAU A 164 - 268 Jmol OpenAstexViewer
B 164 - 268 Jmol OpenAstexViewer
C 164 - 268 Jmol OpenAstexViewer
D 164 - 268 Jmol OpenAstexViewer
E 164 - 268 Jmol OpenAstexViewer
5UAV A 164 - 268 Jmol OpenAstexViewer
B 164 - 268 Jmol OpenAstexViewer
C 164 - 268 Jmol OpenAstexViewer
D 164 - 268 Jmol OpenAstexViewer
E 164 - 268 Jmol OpenAstexViewer
5UAW A 164 - 268 Jmol OpenAstexViewer
B 164 - 268 Jmol OpenAstexViewer
C 164 - 268 Jmol OpenAstexViewer
D 164 - 268 Jmol OpenAstexViewer
E 164 - 268 Jmol OpenAstexViewer
5UAX A 164 - 268 Jmol OpenAstexViewer
B 164 - 268 Jmol OpenAstexViewer
C 164 - 268 Jmol OpenAstexViewer
D 164 - 268 Jmol OpenAstexViewer
E 164 - 268 Jmol OpenAstexViewer