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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RADI_HUMAN (P35241)

Summary

This is the summary of UniProt entry RADI_HUMAN (P35241).

Description: Radixin
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 583 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam FERM_N 9 71
Pfam FERM_M 88 206
coiled_coil n/a 158 185
Pfam FERM_C 210 299
disorder n/a 295 298
disorder n/a 301 347
coiled_coil n/a 302 409
low_complexity n/a 324 352
Pfam ERM_helical 337 456
disorder n/a 351 353
disorder n/a 358 363
disorder n/a 365 583
low_complexity n/a 378 408
coiled_coil n/a 414 462
low_complexity n/a 426 442
low_complexity n/a 456 465
low_complexity n/a 470 481
low_complexity n/a 483 496
Pfam ERM_C 507 583
coiled_coil n/a 514 548

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P35241. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPKPINVRVT TMDAELEFAI QPNTTGKQLF DQVVKTVGLR EVWFFGLQYV
50
51
DSKGYSTWLK LNKKVTQQDV KKENPLQFKF RAKFFPEDVS EELIQEITQR
100
101
LFFLQVKEAI LNDEIYCPPE TAVLLASYAV QAKYGDYNKE IHKPGYLAND
150
151
RLLPQRVLEQ HKLTKEQWEE RIQNWHEEHR GMLREDSMME YLKIAQDLEM
200
201
YGVNYFEIKN KKGTELWLGV DALGLNIYEH DDKLTPKIGF PWSEIRNISF
250
251
NDKKFVIKPI DKKAPDFVFY APRLRINKRI LALCMGNHEL YMRRRKPDTI
300
301
EVQQMKAQAR EEKHQKQLER AQLENEKKKR EIAEKEKERI EREKEELMER
350
351
LKQIEEQTIK AQKELEEQTR KALELDQERK RAKEEAERLE KERRAAEEAK
400
401
SAIAKQAADQ MKNQEQLAAE LAEFTAKIAL LEEAKKKKEE EATEWQHKAF
450
451
AAQEDLEKTK EELKTVMSAP PPPPPPPVIP PTENEHDEHD ENNAEASAEL
500
501
SNEGVMNHRS EEERVTETQK NERVKKQLQA LSSELAQARD ETKKTQNDVL
550
551
HAENVKAGRD KYKTLRQIRQ GNTKQRIDEF EAM                  
583
 

Show the unformatted sequence.

Checksums:
CRC64:889687E1D675FFE7
MD5:422f27da790e2edac3b7be1f0c7b8f6a

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;