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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ADA1A_HUMAN (P35348)

Summary

This is the summary of UniProt entry ADA1A_HUMAN (P35348).

Description: Alpha-1A adrenergic receptor
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 466 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
transmembrane n/a 26 52
low_complexity n/a 26 48
Pfam 7tm_1 43 326
transmembrane n/a 64 94
transmembrane n/a 100 122
transmembrane n/a 143 164
transmembrane n/a 184 209
transmembrane n/a 273 298
transmembrane n/a 310 328
disorder n/a 446 447

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P35348. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MVFLSGNASD SSNCTQPPAP VNISKAILLG VILGGLILFG VLGNILVILS
50
51
VACHRHLHSV THYYIVNLAV ADLLLTSTVL PFSAIFEVLG YWAFGRVFCN
100
101
IWAAVDVLCC TASIMGLCII SIDRYIGVSY PLRYPTIVTQ RRGLMALLCV
150
151
WALSLVISIG PLFGWRQPAP EDETICQINE EPGYVLFSAL GSFYLPLAII
200
201
LVMYCRVYVV AKRESRGLKS GLKTDKSDSE QVTLRIHRKN APAGGSGMAS
250
251
AKTKTHFSVR LLKFSREKKA AKTLGIVVGC FVLCWLPFFL VMPIGSFFPD
300
301
FKPSETVFKI VFWLGYLNSC INPIIYPCSS QEFKKAFQNV LRIQCLCRKQ
350
351
SSKHALGYTL HPPSQAVEGQ HKDMVRIPVG SRETFYRISK TDGVCEWKFF
400
401
SSMPRGSARI TVSKDQSSCT TARVRSKSFL QVCCCVGPST PSLDKNHQVP
450
451
TIKVHTISLS ENGEEV                                     
466
 

Show the unformatted sequence.

Checksums:
CRC64:1A50487531DECDF0
MD5:24dc3b59f9707089e81ee874ce901500

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.