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11  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: BTUF_ECOLI (P37028)

Summary

This is the summary of UniProt entry BTUF_ECOLI (P37028).

Description: Vitamin B12-binding protein {ECO:0000255|HAMAP-Rule:MF_01000}
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
Length: 266 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
sig_p n/a 1 22
Pfam Peripla_BP_2 26 227
disorder n/a 126 127
disorder n/a 130 131

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P37028. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAKSLFRALV ALSFLAPLWL NAAPRVITLS PANTELAFAA GITPVGVSSY
50
51
SDYPPQAQKI EQVSTWQGMN LERIVALKPD LVIAWRGGNA ERQVDQLASL
100
101
GIKVMWVDAT SIEQIANALR QLAPWSPQPD KAEQAAQSLL DQYAQLKAQY
150
151
ADKPKKRVFL QFGINPPFTS GKESIQNQVL EVCGGENIFK DSRVPWPQVS
200
201
REQVLARSPQ AIVITGGPDQ IPKIKQYWGE QLKIPVIPLT SDWFERASPR
250
251
IILAAQQLCN ALSQVD                                     
266
 

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Checksums:
CRC64:480F2E620ACD6EA1
MD5:ef641f630db987af456f7d54f7bbfb7a

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Peripla_BP_2 26 - 215 5M2Q B 26 - 215 Show 3D Structure View in InterPro
5M34 A 26 - 215 Show 3D Structure View in InterPro
26 - 216 1N4D B 1004 - 1194 Show 3D Structure View in InterPro
5M29 A 26 - 216 Show 3D Structure View in InterPro
B 26 - 216 Show 3D Structure View in InterPro
5M2Q A 26 - 216 Show 3D Structure View in InterPro
5M34 B 26 - 216 Show 3D Structure View in InterPro
5M3B A 26 - 216 Show 3D Structure View in InterPro
B 26 - 216 Show 3D Structure View in InterPro
26 - 227 1N2Z A 26 - 227 Show 3D Structure View in InterPro
B 26 - 227 Show 3D Structure View in InterPro
1N4A A 4 - 205 Show 3D Structure View in InterPro
B 5004 - 5205 Show 3D Structure View in InterPro
1N4D A 4 - 205 Show 3D Structure View in InterPro
2QI9 F 26 - 227 Show 3D Structure View in InterPro
4DBL E 26 - 227 Show 3D Structure View in InterPro
J 26 - 227 Show 3D Structure View in InterPro
4FI3 F 26 - 227 Show 3D Structure View in InterPro
5OVW A 26 - 227 Show 3D Structure View in InterPro
B 26 - 227 Show 3D Structure View in InterPro
C 26 - 227 Show 3D Structure View in InterPro
D 26 - 227 Show 3D Structure View in InterPro
E 26 - 227 Show 3D Structure View in InterPro
F 26 - 227 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;