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22  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MCM7_YEAST (P38132)

Summary

This is the summary of UniProt entry MCM7_YEAST (P38132).

Description: DNA replication licensing factor MCM7 EC=3.6.4.12
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (NCBI taxonomy ID 559292)
Length: 845 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam MCM_N 18 206
disorder n/a 35 53
low_complexity n/a 40 53
disorder n/a 153 155
disorder n/a 158 180
disorder n/a 182 184
Pfam MCM_OB 226 359
Pfam MCM 397 620
low_complexity n/a 426 449
disorder n/a 614 616
disorder n/a 629 630
Pfam MCM_lid 636 724
disorder n/a 729 735
disorder n/a 805 806
disorder n/a 814 831
disorder n/a 834 836

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P38132. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSAALPSIQL PVDYNNLFNE ITDFLVTFKQ DTLSSDATRN ENEDENLDAE
50
51
NIEQHLLEKG PKYMAMLQKV ANRELNSVII DLDDILQYQN EKFLQGTQAD
100
101
DLVSAIQQNA NHFTELFCRA IDNNMPLPTK EIDYKDDVLD VILNQRRLRN
150
151
ERMLSDRTNE IRSENLMDTT MDPPSSMNDA LREVVEDETE LFPPNLTRRY
200
201
FLYFKPLSQN CARRYRKKAI SSKPLSVRQI KGDFLGQLIT VRGIITRVSD
250
251
VKPAVEVIAY TCDQCGYEVF QEVNSRTFTP LSECTSEECS QNQTKGQLFM
300
301
STRASKFSAF QECKIQELSQ QVPVGHIPRS LNIHVNGTLV RSLSPGDIVD
350
351
VTGIFLPAPY TGFKALKAGL LTETYLEAQF VRQHKKKFAS FSLTSDVEER
400
401
VMELITSGDV YNRLAKSIAP EIYGNLDVKK ALLLLLVGGV DKRVGDGMKI
450
451
RGDINVCLMG DPGVAKSQLL KAICKISPRG VYTTGKGSSG VGLTAAVMKD
500
501
PVTDEMILEG GALVLADNGI CCIDEFDKMD ESDRTAIHEV MEQQTISISK
550
551
AGINTTLNAR TSILAAANPL YGRYNPRLSP LDNINLPAAL LSRFDILFLM
600
601
LDIPSRDDDE KLAEHVTYVH MHNKQPDLDF TPVEPSKMRE YIAYAKTKRP
650
651
VMSEAVNDYV VQAYIRLRQD SKREMDSKFS FGQATPRTLL GIIRLSQALA
700
701
KLRLADMVDI DDVEEALRLV RVSKESLYQE TNKSKEDESP TTKIFTIIKK
750
751
MLQETGKNTL SYENIVKTVR LRGFTMLQLS NCIQEYSYLN VWHLINEGNT
800
801
LKFVDDGTMD TDQEDSLVST PKLAPQTTAS ANVSAQDSDI DLQDA     
845
 

Show the unformatted sequence.

Checksums:
CRC64:ADA66C719D96DB4A
MD5:eeb91e69600c69f9e17e52f92e2728e9

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
MCM 397 - 620 3JA8 7 397 - 620 Show 3D Structure View in InterPro
3JC5 7 397 - 620 Show 3D Structure View in InterPro
3JC7 7 397 - 620 Show 3D Structure View in InterPro
5BK4 7 397 - 620 Show 3D Structure View in InterPro
F 397 - 620 Show 3D Structure View in InterPro
5U8S 7 397 - 620 Show 3D Structure View in InterPro
5U8T 7 397 - 620 Show 3D Structure View in InterPro
5V8F 7 397 - 620 Show 3D Structure View in InterPro
5XF8 7 397 - 620 Show 3D Structure View in InterPro
6EYC 7 397 - 620 Show 3D Structure View in InterPro
6F0L 7 397 - 620 Show 3D Structure View in InterPro
F 397 - 620 Show 3D Structure View in InterPro
6HV9 7 397 - 620 Show 3D Structure View in InterPro
6PTN 7 397 - 620 Show 3D Structure View in InterPro
n 397 - 620 Show 3D Structure View in InterPro
6PTO 7 397 - 620 Show 3D Structure View in InterPro
K 397 - 620 Show 3D Structure View in InterPro
m 397 - 620 Show 3D Structure View in InterPro
6RQC 7 397 - 620 Show 3D Structure View in InterPro
6SKL 7 397 - 620 Show 3D Structure View in InterPro
6SKO 7 397 - 620 Show 3D Structure View in InterPro
6U0M 7 397 - 620 Show 3D Structure View in InterPro
6WGF 7 397 - 620 Show 3D Structure View in InterPro
6WGG 7 397 - 620 Show 3D Structure View in InterPro
6WGI 7 397 - 620 Show 3D Structure View in InterPro
MCM_lid 636 - 724 3JA8 7 636 - 724 Show 3D Structure View in InterPro
3JC5 7 636 - 724 Show 3D Structure View in InterPro
3JC7 7 636 - 724 Show 3D Structure View in InterPro
5BK4 7 636 - 724 Show 3D Structure View in InterPro
F 636 - 724 Show 3D Structure View in InterPro
5U8S 7 636 - 724 Show 3D Structure View in InterPro
5U8T 7 636 - 724 Show 3D Structure View in InterPro
5V8F 7 636 - 724 Show 3D Structure View in InterPro
5XF8 7 636 - 724 Show 3D Structure View in InterPro
6EYC 7 636 - 724 Show 3D Structure View in InterPro
6F0L 7 636 - 724 Show 3D Structure View in InterPro
F 636 - 724 Show 3D Structure View in InterPro
6HV9 7 636 - 724 Show 3D Structure View in InterPro
6PTN 7 636 - 724 Show 3D Structure View in InterPro
n 636 - 724 Show 3D Structure View in InterPro
6PTO 7 636 - 724 Show 3D Structure View in InterPro
K 636 - 724 Show 3D Structure View in InterPro
m 636 - 724 Show 3D Structure View in InterPro
6RQC 7 636 - 724 Show 3D Structure View in InterPro
6SKL 7 636 - 724 Show 3D Structure View in InterPro
6SKO 7 636 - 724 Show 3D Structure View in InterPro
6U0M 7 636 - 724 Show 3D Structure View in InterPro
6WGF 7 636 - 724 Show 3D Structure View in InterPro
6WGG 7 636 - 724 Show 3D Structure View in InterPro
6WGI 7 636 - 724 Show 3D Structure View in InterPro
MCM_N 18 - 206 3JA8 7 18 - 206 Show 3D Structure View in InterPro
3JC5 7 18 - 206 Show 3D Structure View in InterPro
3JC6 7 18 - 206 Show 3D Structure View in InterPro
3JC7 7 18 - 206 Show 3D Structure View in InterPro
5BK4 7 18 - 206 Show 3D Structure View in InterPro
F 18 - 206 Show 3D Structure View in InterPro
5U8S 7 18 - 206 Show 3D Structure View in InterPro
5U8T 7 18 - 206 Show 3D Structure View in InterPro
5V8F 7 18 - 206 Show 3D Structure View in InterPro
5XF8 7 18 - 206 Show 3D Structure View in InterPro
6EYC 7 18 - 206 Show 3D Structure View in InterPro
6F0L 7 18 - 206 Show 3D Structure View in InterPro
F 18 - 206 Show 3D Structure View in InterPro
6HV9 7 18 - 206 Show 3D Structure View in InterPro
6PTJ 7 18 - 206 Show 3D Structure View in InterPro
6PTN 7 18 - 206 Show 3D Structure View in InterPro
n 18 - 206 Show 3D Structure View in InterPro
6PTO 7 18 - 206 Show 3D Structure View in InterPro
K 18 - 206 Show 3D Structure View in InterPro
m 18 - 206 Show 3D Structure View in InterPro
6RQC 7 18 - 206 Show 3D Structure View in InterPro
6SKL 7 18 - 206 Show 3D Structure View in InterPro
6U0M 7 18 - 206 Show 3D Structure View in InterPro
6WGG 7 18 - 206 Show 3D Structure View in InterPro
6WGI 7 18 - 206 Show 3D Structure View in InterPro
59 - 206 6WGF 7 59 - 206 Show 3D Structure View in InterPro
MCM_OB 226 - 356 6WGF 7 226 - 356 Show 3D Structure View in InterPro
6WGG 7 226 - 356 Show 3D Structure View in InterPro
6WGI 7 226 - 356 Show 3D Structure View in InterPro
226 - 359 3JA8 7 226 - 359 Show 3D Structure View in InterPro
3JC5 7 226 - 359 Show 3D Structure View in InterPro
3JC6 7 226 - 359 Show 3D Structure View in InterPro
3JC7 7 226 - 359 Show 3D Structure View in InterPro
5BK4 7 226 - 359 Show 3D Structure View in InterPro
F 226 - 359 Show 3D Structure View in InterPro
5U8S 7 226 - 359 Show 3D Structure View in InterPro
5U8T 7 226 - 359 Show 3D Structure View in InterPro
5V8F 7 226 - 359 Show 3D Structure View in InterPro
5XF8 7 226 - 359 Show 3D Structure View in InterPro
6EYC 7 226 - 359 Show 3D Structure View in InterPro
6F0L 7 226 - 359 Show 3D Structure View in InterPro
F 226 - 359 Show 3D Structure View in InterPro
6HV9 7 226 - 359 Show 3D Structure View in InterPro
6PTJ 7 226 - 359 Show 3D Structure View in InterPro
6PTN 7 226 - 359 Show 3D Structure View in InterPro
n 226 - 359 Show 3D Structure View in InterPro
6PTO 7 226 - 359 Show 3D Structure View in InterPro
K 226 - 359 Show 3D Structure View in InterPro
m 226 - 359 Show 3D Structure View in InterPro
6RQC 7 226 - 359 Show 3D Structure View in InterPro
6SKL 7 226 - 359 Show 3D Structure View in InterPro
6U0M 7 226 - 359 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;