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9  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: S61A1_CANLF (P38377)

Summary

This is the summary of UniProt entry S61A1_CANLF (P38377).

Description: Protein transport protein Sec61 subunit alpha isoform 1
Source organism: Canis lupus familiaris (Dog) (Canis familiaris) (NCBI taxonomy ID 9615)
View Pfam proteome data.
Length: 476 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
transmembrane n/a 32 54
Pfam Plug_translocon 40 74
transmembrane n/a 74 97
Pfam SecY 75 458
transmembrane n/a 118 137
transmembrane n/a 143 165
transmembrane n/a 172 193
transmembrane n/a 205 221
transmembrane n/a 242 263
transmembrane n/a 283 303
transmembrane n/a 413 431
transmembrane n/a 437 458

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P38377. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAIKFLEVIK PFCVILPEIQ KPERKIQFKE KVLWTAITLF IFLVCCQIPL
50
51
FGIMSSDSAD PFYWMRVILA SNRGTLMELG ISPIVTSGLI MQLLAGAKII
100
101
EVGDTPKDRA LFNGAQKLFG MIITIGQSIV YVMTGMYGDP SEMGAGICLL
150
151
ITIQLFVAGL IVLLLDELLQ KGYGLGSGIS LFIATNICET IVWKAFSPTT
200
201
VNTGRGMEFE GAIIALFHLL ATRTDKVRAL REAFYRQNLP NLMNLIATIF
250
251
VFAVVIYFQG FRVDLPIKSA RYRGQYNTYP IKLFYTSNIP IILQSALVSN
300
301
LYVISQMLSA RFSGNLLVSL LGTWSDTSSG GPARAYPVGG LCHYLSPPES
350
351
FGSVLEDPVH AVVYIVFMLG SCAFFSKTWI EVSGSSAKDV AKQLKEQQMV
400
401
MRGHRETSMV HELNRYIPTA AAFGGLCIGA LSVLADFLGA IGSGTGILLA
450
451
VTIIYQYFEI FVKEQSEVGS MGALLF                          
476
 

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Checksums:
CRC64:B1A9B7A6697327FE
MD5:acc465e4e688f553ec1862bf7fda48cc

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Plug_translocon 40 - 74 2WWB A 40 - 74 Jmol OpenAstexViewer
3JC2 1 40 - 74 Jmol OpenAstexViewer
4CG5 A 40 - 74 Jmol OpenAstexViewer
4CG6 A 40 - 74 Jmol OpenAstexViewer
4CG7 A 40 - 74 Jmol OpenAstexViewer
5A6U A 40 - 74 Jmol OpenAstexViewer
6FTG x 40 - 74 Jmol OpenAstexViewer
6FTI x 40 - 74 Jmol OpenAstexViewer
6FTJ x 40 - 74 Jmol OpenAstexViewer
SecY 75 - 458 2WWB A 75 - 458 Jmol OpenAstexViewer
3JC2 1 75 - 458 Jmol OpenAstexViewer
4CG5 A 75 - 458 Jmol OpenAstexViewer
4CG6 A 75 - 458 Jmol OpenAstexViewer
4CG7 A 75 - 458 Jmol OpenAstexViewer
5A6U A 75 - 458 Jmol OpenAstexViewer
6FTG x 75 - 458 Jmol OpenAstexViewer
6FTI x 75 - 458 Jmol OpenAstexViewer
6FTJ x 75 - 458 Jmol OpenAstexViewer