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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: LICH_HUMAN (P38571)

Summary

This is the summary of UniProt entry LICH_HUMAN (P38571).

Description: Lysosomal acid lipase/cholesteryl ester hydrolase EC=3.1.1.13
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 399 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 21
Pfam Abhydrolase_1 80 381
low_complexity n/a 255 267

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P38571. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKMRFLGLVV CLVLWTLHSE GSGGKLTAVD PETNMNVSEI ISYWGFPSEE
50
51
YLVETEDGYI LCLNRIPHGR KNHSDKGPKP VVFLQHGLLA DSSNWVTNLA
100
101
NSSLGFILAD AGFDVWMGNS RGNTWSRKHK TLSVSQDEFW AFSYDEMAKY
150
151
DLPASINFIL NKTGQEQVYY VGHSQGTTIG FIAFSQIPEL AKRIKMFFAL
200
201
GPVASVAFCT SPMAKLGRLP DHLIKDLFGD KEFLPQSAFL KWLGTHVCTH
250
251
VILKELCGNL CFLLCGFNER NLNMSRVDVY TTHSPAGTSV QNMLHWSQAV
300
301
KFQKFQAFDW GSSAKNYFHY NQSYPPTYNV KDMLVPTAVW SGGHDWLADV
350
351
YDVNILLTQI TNLVFHESIP EWEHLDFIWG LDAPWRLYNK IINLMRKYQ 
399
 

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Checksums:
CRC64:AC75A7909DA9195A
MD5:e521fde1f0dd1582c9eb1f76a762d235

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.