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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ETV4_HUMAN (P43268)

Summary

This is the summary of UniProt entry ETV4_HUMAN (P43268).

Description: ETS translocation variant 4
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 484 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 4
Pfam ETS_PEA3_N 5 339
disorder n/a 12 25
disorder n/a 29 36
disorder n/a 38 48
disorder n/a 50 52
disorder n/a 64 66
disorder n/a 68 69
disorder n/a 71 85
disorder n/a 88 114
disorder n/a 121 124
disorder n/a 135 181
disorder n/a 189 193
disorder n/a 195 222
disorder n/a 224 255
disorder n/a 290 294
disorder n/a 296 299
disorder n/a 328 329
Pfam Ets 342 421
disorder n/a 442 444
disorder n/a 451 453

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P43268. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MERRMKAGYL DQQVPYTFSS KSPGNGSLRE ALIGPLGKLM DPGSLPPLDS
50
51
EDLFQDLSHF QETWLAEAQV PDSDEQFVPD FHSENLAFHS PTTRIKKEPQ
100
101
SPRTDPALSC SRKPPLPYHH GEQCLYSSAY DPPRQIAIKS PAPGALGQSP
150
151
LQPFPRAEQR NFLRSSGTSQ PHPGHGYLGE HSSVFQQPLD ICHSFTSQGG
200
201
GREPLPAPYQ HQLSEPCPPY PQQSFKQEYH DPLYEQAGQP AVDQGGVNGH
250
251
RYPGAGVVIK QEQTDFAYDS DVTGCASMYL HTEGFSGPSP GDGAMGYGYE
300
301
KPLRPFPDDV CVVPEKFEGD IKQEGVGAFR EGPPYQRRGA LQLWQFLVAL
350
351
LDDPTNAHFI AWTGRGMEFK LIEPEEVARL WGIQKNRPAM NYDKLSRSLR
400
401
YYYEKGIMQK VAGERYVYKF VCEPEALFSL AFPDNQRPAL KAEFDRPVSE
450
451
EDTVPLSHLD ESPAYLPELA GPAQPFGPKG GYSY                 
484
 

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Checksums:
CRC64:BA9864F3C690A8C1
MD5:825de6c3c9bde938ea4c67002308fe72

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Ets 342 - 421 4CO8 A 342 - 421 Jmol OpenAstexViewer
4UUV A 342 - 421 Jmol OpenAstexViewer
D 342 - 421 Jmol OpenAstexViewer
G 342 - 421 Jmol OpenAstexViewer
J 342 - 421 Jmol OpenAstexViewer
M 342 - 421 Jmol OpenAstexViewer
P 342 - 421 Jmol OpenAstexViewer
S 342 - 421 Jmol OpenAstexViewer
V 342 - 421 Jmol OpenAstexViewer
5ILU A 342 - 421 Jmol OpenAstexViewer
ETS_PEA3_N 338 - 339 4CO8 A 338 - 339 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.