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5  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RAD52_HUMAN (P43351)

Summary

This is the summary of UniProt entry RAD52_HUMAN (P43351).

Description: DNA repair protein RAD52 homolog
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 418 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 5 6
disorder n/a 9 11
Pfam Rad52_Rad22 35 183
disorder n/a 186 193
disorder n/a 195 310
low_complexity n/a 239 250
low_complexity n/a 255 266
low_complexity n/a 281 294
disorder n/a 316 317
disorder n/a 319 320
disorder n/a 324 418

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P43351. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSGTEEAILG GRDSHPAAGG GSVLCFGQCQ YTAEEYQAIQ KALRQRLGPE
50
51
YISSRMAGGG QKVCYIEGHR VINLANEMFG YNGWAHSITQ QNVDFVDLNN
100
101
GKFYVGVCAF VRVQLKDGSY HEDVGYGVSE GLKSKALSLE KARKEAVTDG
150
151
LKRALRSFGN ALGNCILDKD YLRSLNKLPR QLPLEVDLTK AKRQDLEPSV
200
201
EEARYNSCRP NMALGHPQLQ QVTSPSRPSH AVIPADQDCS SRSLSSSAVE
250
251
SEATHQRKLR QKQLQQQFRE RMEKQQVRVS TPSAEKSEAA PPAPPVTHST
300
301
PVTVSEPLLE KDFLAGVTQE LIKTLEDNSE KWAVTPDAGD GVVKPSSRAD
350
351
PAQTSDTLAL NNQMVTQNRT PHSVCHQKPQ AKSGSWDLQT YSADQRTTGN
400
401
WESHRKSQDM KKRKYDPS                                   
418
 

Show the unformatted sequence.

Checksums:
CRC64:7E1BBCAF0B9CD4AF
MD5:571c61e3784b611dacecd25b99c5815d

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Rad52_Rad22 35 - 183 1H2I A 35 - 183 Jmol OpenAstexViewer
B 35 - 183 Jmol OpenAstexViewer
C 35 - 183 Jmol OpenAstexViewer
D 35 - 183 Jmol OpenAstexViewer
E 35 - 183 Jmol OpenAstexViewer
F 35 - 183 Jmol OpenAstexViewer
G 35 - 183 Jmol OpenAstexViewer
H 35 - 183 Jmol OpenAstexViewer
I 35 - 183 Jmol OpenAstexViewer
J 35 - 183 Jmol OpenAstexViewer
K 35 - 183 Jmol OpenAstexViewer
L 35 - 183 Jmol OpenAstexViewer
M 35 - 183 Jmol OpenAstexViewer
N 35 - 183 Jmol OpenAstexViewer
O 35 - 183 Jmol OpenAstexViewer
P 35 - 183 Jmol OpenAstexViewer
Q 35 - 183 Jmol OpenAstexViewer
R 35 - 183 Jmol OpenAstexViewer
S 35 - 183 Jmol OpenAstexViewer
T 35 - 183 Jmol OpenAstexViewer
U 35 - 183 Jmol OpenAstexViewer
V 35 - 183 Jmol OpenAstexViewer
1KN0 A 35 - 183 Jmol OpenAstexViewer
B 35 - 183 Jmol OpenAstexViewer
C 35 - 183 Jmol OpenAstexViewer
D 35 - 183 Jmol OpenAstexViewer
E 35 - 183 Jmol OpenAstexViewer
F 35 - 183 Jmol OpenAstexViewer
G 35 - 183 Jmol OpenAstexViewer
H 35 - 183 Jmol OpenAstexViewer
I 35 - 183 Jmol OpenAstexViewer
J 35 - 183 Jmol OpenAstexViewer
K 35 - 183 Jmol OpenAstexViewer
5JRB A 35 - 183 Jmol OpenAstexViewer
B 35 - 183 Jmol OpenAstexViewer
C 35 - 183 Jmol OpenAstexViewer
D 35 - 183 Jmol OpenAstexViewer
E 35 - 183 Jmol OpenAstexViewer
F 35 - 183 Jmol OpenAstexViewer
G 35 - 183 Jmol OpenAstexViewer
H 35 - 183 Jmol OpenAstexViewer
I 35 - 183 Jmol OpenAstexViewer
J 35 - 183 Jmol OpenAstexViewer
K 35 - 183 Jmol OpenAstexViewer
5XRZ A 35 - 183 Jmol OpenAstexViewer
B 35 - 183 Jmol OpenAstexViewer
C 35 - 183 Jmol OpenAstexViewer
D 35 - 183 Jmol OpenAstexViewer
E 35 - 183 Jmol OpenAstexViewer
F 35 - 183 Jmol OpenAstexViewer
G 35 - 183 Jmol OpenAstexViewer
H 35 - 183 Jmol OpenAstexViewer
I 35 - 183 Jmol OpenAstexViewer
J 35 - 183 Jmol OpenAstexViewer
K 35 - 183 Jmol OpenAstexViewer
5XS0 A 35 - 183 Jmol OpenAstexViewer
B 35 - 183 Jmol OpenAstexViewer
C 35 - 183 Jmol OpenAstexViewer
D 35 - 183 Jmol OpenAstexViewer
E 35 - 183 Jmol OpenAstexViewer
F 35 - 183 Jmol OpenAstexViewer
G 35 - 183 Jmol OpenAstexViewer
H 35 - 183 Jmol OpenAstexViewer
I 35 - 183 Jmol OpenAstexViewer
J 35 - 183 Jmol OpenAstexViewer
K 35 - 183 Jmol OpenAstexViewer
L 35 - 183 Jmol OpenAstexViewer
M 35 - 183 Jmol OpenAstexViewer
N 35 - 183 Jmol OpenAstexViewer
O 35 - 183 Jmol OpenAstexViewer
P 35 - 183 Jmol OpenAstexViewer
Q 35 - 183 Jmol OpenAstexViewer
R 35 - 183 Jmol OpenAstexViewer
S 35 - 183 Jmol OpenAstexViewer
T 35 - 183 Jmol OpenAstexViewer
U 35 - 183 Jmol OpenAstexViewer
V 35 - 183 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.