Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: THI5_YEAST (P43534)

Summary

This is the summary of UniProt entry THI5_YEAST (P43534).

Description: 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI5 {ECO:0000303|PubMed:23048037}
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (NCBI taxonomy ID 559292)
View Pfam proteome data.
Length: 340 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam NMT1 15 238

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P43534. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSTDKITFLL NWQPTPYHIP IFLAQTKGYF KEQGLDMAIL EPTNPSDVTE
50
51
LIGSGKVDMG LKAMIHTLAA KARGFPVTSV ASLLDEPFTG VLYLKGSGIT
100
101
EDFQSLKGKK IGYVGEFGKI QIDELTKHYG MKPEDYTAVR CGMNVAKYII
150
151
EGKIDAGIGI ECMQQVELEE YLAKQGRPAS DAKMLRIDKL ACLGCCCFCT
200
201
VLYICNDEFL KKNPEKVRKF LKAIKKATDY VLADPVKAWK EYIDFKPQLN
250
251
NDLSYKQYQR CYAYFSSSLY NVHRDWKKVT GYGKRLAILP PDYVSNYTNE
300
301
YLSWPEPEEV SDPLEAQRLM AIHQEKCRQE GTFKRLALPA           
340
 

Show the unformatted sequence.

Checksums:
CRC64:D810C5D5A86FA6C0
MD5:942f5d69d321f43289f8314e3db15caf

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
NMT1 15 - 238 4H65 A 15 - 238 Jmol OpenAstexViewer
B 15 - 238 Jmol OpenAstexViewer
4H67 A 15 - 238 Jmol OpenAstexViewer
B 15 - 238 Jmol OpenAstexViewer
C 15 - 238 Jmol OpenAstexViewer
D 15 - 238 Jmol OpenAstexViewer
E 15 - 238 Jmol OpenAstexViewer
F 15 - 238 Jmol OpenAstexViewer
G 15 - 238 Jmol OpenAstexViewer
H 15 - 238 Jmol OpenAstexViewer
4H6D A 15 - 238 Jmol OpenAstexViewer
B 15 - 238 Jmol OpenAstexViewer
C 15 - 238 Jmol OpenAstexViewer
D 15 - 238 Jmol OpenAstexViewer
E 15 - 238 Jmol OpenAstexViewer
F 15 - 238 Jmol OpenAstexViewer
G 15 - 238 Jmol OpenAstexViewer
H 15 - 238 Jmol OpenAstexViewer