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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: AL1A3_HUMAN (P47895)

Summary

This is the summary of UniProt entry AL1A3_HUMAN (P47895).

Description: Aldehyde dehydrogenase family 1 member A3
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 512 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 23
Pfam Aldedh 40 503
disorder n/a 46 49
disorder n/a 58 68
disorder n/a 74 76
disorder n/a 348 350

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P47895. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MATANGAVEN GQPDRKPPAL PRPIRNLEVK FTKIFINNEW HESKSGKKFA
50
51
TCNPSTREQI CEVEEGDKPD VDKAVEAAQV AFQRGSPWRR LDALSRGRLL
100
101
HQLADLVERD RATLAALETM DTGKPFLHAF FIDLEGCIRT LRYFAGWADK
150
151
IQGKTIPTDD NVVCFTRHEP IGVCGAITPW NFPLLMLVWK LAPALCCGNT
200
201
MVLKPAEQTP LTALYLGSLI KEAGFPPGVV NIVPGFGPTV GAAISSHPQI
250
251
NKIAFTGSTE VGKLVKEAAS RSNLKRVTLE LGGKNPCIVC ADADLDLAVE
300
301
CAHQGVFFNQ GQCCTAASRV FVEEQVYSEF VRRSVEYAKK RPVGDPFDVK
350
351
TEQGPQIDQK QFDKILELIE SGKKEGAKLE CGGSAMEDKG LFIKPTVFSE
400
401
VTDNMRIAKE EIFGPVQPIL KFKSIEEVIK RANSTDYGLT AAVFTKNLDK
450
451
ALKLASALES GTVWINCYNA LYAQAPFGGF KMSGNGRELG EYALAEYTEV
500
501
KTVTIKLGDK NP                                         
512
 

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Checksums:
CRC64:1BFCF4F56F0FE89A
MD5:caf7925a9970bfd52bc7d905e4abfcee

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Aldedh 40 - 503 5FHZ A 40 - 503 Jmol OpenAstexViewer
B 40 - 503 Jmol OpenAstexViewer
C 40 - 503 Jmol OpenAstexViewer
D 40 - 503 Jmol OpenAstexViewer
E 40 - 503 Jmol OpenAstexViewer
F 40 - 503 Jmol OpenAstexViewer
G 40 - 503 Jmol OpenAstexViewer
H 40 - 503 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.