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17  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: KCNJ6_MOUSE (P48542)

Summary

This is the summary of UniProt entry KCNJ6_MOUSE (P48542).

Description: G protein-activated inward rectifier potassium channel 2
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
View Pfam proteome data.
Length: 425 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 40 43
Pfam IRK 59 198
transmembrane n/a 95 119
transmembrane n/a 131 149
transmembrane n/a 169 193
Pfam IRK_C 205 377
low_complexity n/a 301 314
disorder n/a 367 369
disorder n/a 392 425
low_complexity n/a 395 410

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P48542. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTMAKLTESM TNVLEGDSMD QDVESPVAIH QPKLPKQARD DLPRHISRDR
50
51
TKRKIQRYVR KDGKCNVHHG NVRETYRYLT DIFTTLVDLK WRFNLLIFVM
100
101
VYTVTWLFFG MIWWLIAYIR GDMDHIEDPS WTPCVTNLNG FVSAFLFSIE
150
151
TETTIGYGYR VITDKCPEGI ILLLIQSVLG SIVNAFMVGC MFVKISQPKK
200
201
RAETLVFSTH AVISMRDGKL CLMFRVGDLR NSHIVEASIR AKLIKSKQTS
250
251
EGEFIPLNQS DINVGYYTGD DRLFLVSPLI ISHEINQQSP FWEISKAQLP
300
301
KEELEIVVIL EGIVEATGMT CQARSSYITS EILWGYRFTP VLTMEDGFYE
350
351
VDYNSFHETY ETSTPSLSAK ELAELANRAE VPLSWSVSSK LNQHAELETE
400
401
EEEKNPEELT ERNGDVANLE NESKV                           
425
 

Show the unformatted sequence.

Checksums:
CRC64:2E5153DCB1B60331
MD5:d6fbc4fe453d22483e16db08f46dd75c

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
IRK 59 - 198 3SYA A 59 - 198 Jmol OpenAstexViewer
3SYC A 59 - 198 Jmol OpenAstexViewer
3SYO A 59 - 198 Jmol OpenAstexViewer
3SYP A 59 - 198 Jmol OpenAstexViewer
3SYQ A 59 - 198 Jmol OpenAstexViewer
B 59 - 198 Jmol OpenAstexViewer
4KFM A 59 - 198 Jmol OpenAstexViewer
59 - 71 3AUW A 59 - 71 Jmol OpenAstexViewer
C 59 - 71 Jmol OpenAstexViewer
59 - 92 3AGW A 59 - 216 Jmol OpenAstexViewer
IRK_C 205 - 377 2E4F A 205 - 377 Jmol OpenAstexViewer
3AT8 A 205 - 377 Jmol OpenAstexViewer
3AT9 A 205 - 377 Jmol OpenAstexViewer
3ATA A 205 - 377 Jmol OpenAstexViewer
3ATB A 205 - 377 Jmol OpenAstexViewer
3ATD A 205 - 377 Jmol OpenAstexViewer
3ATE A 205 - 377 Jmol OpenAstexViewer
3ATF A 205 - 377 Jmol OpenAstexViewer
3AUW B 205 - 377 Jmol OpenAstexViewer
D 205 - 377 Jmol OpenAstexViewer
3SYA A 205 - 377 Jmol OpenAstexViewer
3SYC A 205 - 377 Jmol OpenAstexViewer
3SYO A 205 - 377 Jmol OpenAstexViewer
3SYP A 205 - 377 Jmol OpenAstexViewer
3SYQ A 205 - 377 Jmol OpenAstexViewer
B 205 - 377 Jmol OpenAstexViewer
3VSQ A 205 - 377 Jmol OpenAstexViewer
4KFM A 205 - 377 Jmol OpenAstexViewer
217 - 377 3AGW A 217 - 377 Jmol OpenAstexViewer