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6  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PRP31_YEAST (P49704)

Summary

This is the summary of UniProt entry PRP31_YEAST (P49704).

Description: Pre-mRNA-processing factor 31
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (NCBI taxonomy ID 559292)
Length: 494 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
low_complexity n/a 4 18
disorder n/a 27 28
Pfam Nop 101 343
disorder n/a 327 332
disorder n/a 348 373
Pfam Prp31_C 350 481
disorder n/a 386 388
disorder n/a 390 393
disorder n/a 395 396
disorder n/a 404 409
disorder n/a 411 494

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P49704. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSSEEDYFDE LEYDLADEVN EEKEDIQTKK LTTVNCQTEK FNPFEILPES
50
51
IELFRTLALI SPDRLSLSET AQILPKIVDL KRILQQQEID FIKLLPFFNE
100
101
IIPLIKSNIK LMHNFLISLY SRRFPELSSL IPSPLQYSKV ISILENENYS
150
151
KNESDELFFH LENKAKLTRE QILVLTMSMK TSFKNKEPLD IKTRTQILEA
200
201
NSILENLWKL QEDIGQYIAS KISIIAPNVC FLVGPEIAAQ LIAHAGGVLE
250
251
FSRIPSCNIA SIGKNKHLSH ELHTLESGVR QEGYLFASDM IQKFPVSVHK
300
301
QMLRMLCAKV SLAARVDAGQ KNGDRNTVLA HKWKAELSKK ARKLSEAPSI
350
351
SETKALPIPE DQPKKKRAGR KFRKYKEKFR LSHVRQLQNR MEFGKQEQTV
400
401
LDSYGEEVGL GMSNTSLQQA VGATSGSRRS AGNQAKLTKV MKHRISEANQ
450
451
QADEFLISLG HNTEQPNLSP EMVQMHKKQH TNPEEETNWF SGHG      
494
 

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Checksums:
CRC64:E39AC6247859FB3B
MD5:4ae2aabc69e4d2872fab50ea097a5ed6

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Nop 101 - 343 3JCM I 101 - 343 Show 3D Structure View in InterPro
5GAN F 101 - 343 Show 3D Structure View in InterPro
5GAP F 101 - 343 Show 3D Structure View in InterPro
5NRL F 101 - 343 Show 3D Structure View in InterPro
5ZWM L 101 - 343 Show 3D Structure View in InterPro
5ZWO L 101 - 343 Show 3D Structure View in InterPro
Prp31_C 350 - 457 5GAN F 350 - 457 Show 3D Structure View in InterPro
5GAP F 350 - 457 Show 3D Structure View in InterPro
350 - 458 5NRL F 350 - 458 Show 3D Structure View in InterPro
350 - 462 3JCM I 350 - 462 Show 3D Structure View in InterPro
5ZWM L 350 - 462 Show 3D Structure View in InterPro
5ZWO L 350 - 462 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;