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48  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PSB2_HUMAN (P49721)

Summary

This is the summary of UniProt entry PSB2_HUMAN (P49721).

Description: Proteasome subunit beta type-2
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 201 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam Proteasome 3 183
low_complexity n/a 114 127
low_complexity n/a 122 131

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P49721. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEYLIGIQGP DYVLVASDRV AASNIVQMKD DHDKMFKMSE KILLLCVGEA
50
51
GDTVQFAEYI QKNVQLYKMR NGYELSPTAA ANFTRRNLAD CLRSRTPYHV
100
101
NLLLAGYDEH EGPALYYMDY LAALAKAPFA AHGYGAFLTL SILDRYYTPT
150
151
ISRERAVELL RKCLEELQKR FILNLPTFSV RIIDKNGIHD LDNISFPKQG
200
201
S                                                     
201
 

Show the unformatted sequence.

Checksums:
CRC64:04D085D7BAA76130
MD5:ff255c6b9baa4bf77aa7373619708c40

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Proteasome 3 - 183 4R3O K 3 - 183 Show 3D Structure View in InterPro
Y 3 - 183 Show 3D Structure View in InterPro
4R67 n/a 3 - 183 Show 3D Structure View in InterPro
K 3 - 183 Show 3D Structure View in InterPro
m 3 - 183 Show 3D Structure View in InterPro
Y 3 - 183 Show 3D Structure View in InterPro
5A0Q K 3 - 183 Show 3D Structure View in InterPro
Y 3 - 183 Show 3D Structure View in InterPro
5GJQ d 3 - 183 Show 3D Structure View in InterPro
r 3 - 183 Show 3D Structure View in InterPro
5GJR d 3 - 183 Show 3D Structure View in InterPro
r 3 - 183 Show 3D Structure View in InterPro
5L4G 2 3 - 183 Show 3D Structure View in InterPro
V 3 - 183 Show 3D Structure View in InterPro
5LE5 J 3 - 183 Show 3D Structure View in InterPro
X 3 - 183 Show 3D Structure View in InterPro
5LEX J 3 - 183 Show 3D Structure View in InterPro
X 3 - 183 Show 3D Structure View in InterPro
5LEY J 3 - 183 Show 3D Structure View in InterPro
X 3 - 183 Show 3D Structure View in InterPro
5LEZ J 3 - 183 Show 3D Structure View in InterPro
X 3 - 183 Show 3D Structure View in InterPro
5LF0 J 3 - 183 Show 3D Structure View in InterPro
X 3 - 183 Show 3D Structure View in InterPro
5LF1 J 3 - 183 Show 3D Structure View in InterPro
X 3 - 183 Show 3D Structure View in InterPro
5LF3 J 3 - 183 Show 3D Structure View in InterPro
X 3 - 183 Show 3D Structure View in InterPro
5LF4 J 3 - 183 Show 3D Structure View in InterPro
X 3 - 183 Show 3D Structure View in InterPro
5LF6 J 3 - 183 Show 3D Structure View in InterPro
X 3 - 183 Show 3D Structure View in InterPro
5LF7 J 3 - 183 Show 3D Structure View in InterPro
X 3 - 183 Show 3D Structure View in InterPro
5LN3 4 3 - 183 Show 3D Structure View in InterPro
5M32 J 3 - 183 Show 3D Structure View in InterPro
X 3 - 183 Show 3D Structure View in InterPro
5T0C AQ 3 - 183 Show 3D Structure View in InterPro
BQ 3 - 183 Show 3D Structure View in InterPro
5T0G Q 3 - 183 Show 3D Structure View in InterPro
5T0H Q 3 - 183 Show 3D Structure View in InterPro
5T0I Q 3 - 183 Show 3D Structure View in InterPro
5T0J Q 3 - 183 Show 3D Structure View in InterPro
5VFO Q 3 - 183 Show 3D Structure View in InterPro
q 3 - 183 Show 3D Structure View in InterPro
5VFP Q 3 - 183 Show 3D Structure View in InterPro
q 3 - 183 Show 3D Structure View in InterPro
5VFQ Q 3 - 183 Show 3D Structure View in InterPro
q 3 - 183 Show 3D Structure View in InterPro
5VFR Q 3 - 183 Show 3D Structure View in InterPro
q 3 - 183 Show 3D Structure View in InterPro
5VFS Q 3 - 183 Show 3D Structure View in InterPro
q 3 - 183 Show 3D Structure View in InterPro
5VFT Q 3 - 183 Show 3D Structure View in InterPro
q 3 - 183 Show 3D Structure View in InterPro
5VFU Q 3 - 183 Show 3D Structure View in InterPro
q 3 - 183 Show 3D Structure View in InterPro
6AVO T 3 - 183 Show 3D Structure View in InterPro
V 3 - 183 Show 3D Structure View in InterPro
6E5B J 3 - 183 Show 3D Structure View in InterPro
X 3 - 183 Show 3D Structure View in InterPro
6KWY J 3 - 183 Show 3D Structure View in InterPro
X 3 - 183 Show 3D Structure View in InterPro
6MSB Q 3 - 183 Show 3D Structure View in InterPro
q 3 - 183 Show 3D Structure View in InterPro
6MSD Q 3 - 183 Show 3D Structure View in InterPro
q 3 - 183 Show 3D Structure View in InterPro
6MSE Q 3 - 183 Show 3D Structure View in InterPro
q 3 - 183 Show 3D Structure View in InterPro
6MSG Q 3 - 183 Show 3D Structure View in InterPro
q 3 - 183 Show 3D Structure View in InterPro
6MSH Q 3 - 183 Show 3D Structure View in InterPro
q 3 - 183 Show 3D Structure View in InterPro
6MSJ Q 3 - 183 Show 3D Structure View in InterPro
q 3 - 183 Show 3D Structure View in InterPro
6MSK Q 3 - 183 Show 3D Structure View in InterPro
q 3 - 183 Show 3D Structure View in InterPro
6R70 J 3 - 183 Show 3D Structure View in InterPro
X 3 - 183 Show 3D Structure View in InterPro
6REY K 3 - 183 Show 3D Structure View in InterPro
Y 3 - 183 Show 3D Structure View in InterPro
6RGQ K 3 - 183 Show 3D Structure View in InterPro
Y 3 - 183 Show 3D Structure View in InterPro
6WJD Q 3 - 183 Show 3D Structure View in InterPro
q 3 - 183 Show 3D Structure View in InterPro
6WJN Q 3 - 183 Show 3D Structure View in InterPro
q 3 - 183 Show 3D Structure View in InterPro
6XMJ K 3 - 183 Show 3D Structure View in InterPro
7AWE K 3 - 183 Show 3D Structure View in InterPro
Y 3 - 183 Show 3D Structure View in InterPro
7NHT J 3 - 183 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;