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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: PA2G4_MOUSE (P50580)

Summary

This is the summary of UniProt entry PA2G4_MOUSE (P50580).

Description: Proliferation-associated protein 2G4
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
View Pfam proteome data.
Length: 394 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 6
disorder n/a 8 9
Pfam Peptidase_M24 19 294
low_complexity n/a 60 73
disorder n/a 197 214
disorder n/a 240 245
disorder n/a 335 340
low_complexity n/a 358 376
disorder n/a 360 361
disorder n/a 365 394

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P50580. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSGEDEQQEQ TIAEDLVVTK YKMGGDIANR VLRSLVEASS SGVSVLSLCE
50
51
KGDAMIMEET GKIFKKEKEM KKGIAFPTSI SVNNCVCHFS PLKSDQDYIL
100
101
KEGDLVKIDL GVHVDGFIAN VAHTFVIGVA QGTQVTGRKA DVIKAAHLCA
150
151
EAALRLVKPG NQNTQVTEAW NKVAHSFNCT PIEGMLSHQL KQHVIDGEKT
200
201
IIQNPTDQQK KDHEKAEFEV HEVYAVDVLV SSGEGKAKDA GQRTTIYKRD
250
251
PSKQYGLKMK TSRAFFSEVE RRFDAMPFTL RAFEDEKKAR MGVVECAKHE
300
301
LLQPFNVLYE KEGEFVAQFK FTVLLMPNGP MRITSGPFEP DLYKSEMEVQ
350
351
DAELKALLQS SASRKTQKKK KKKASKTVEN ATSGETLEEN GAGD      
394
 

Show the unformatted sequence.

Checksums:
CRC64:ABCD169F064261EB
MD5:506ad578a4ecc7e67a7a342fdac60f7b

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Peptidase_M24 19 - 294 2V6C A 19 - 294 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.