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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CLCN6_HUMAN (P51797)

Summary

This is the summary of UniProt entry CLCN6_HUMAN (P51797).

Description: Chloride transport protein 6
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 869 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
low_complexity n/a 2 20
disorder n/a 29 31
transmembrane n/a 81 106
low_complexity n/a 125 137
transmembrane n/a 126 150
Pfam Voltage_CLC 138 570
transmembrane n/a 180 197
transmembrane n/a 203 220
transmembrane n/a 241 264
low_complexity n/a 243 259
transmembrane n/a 276 294
transmembrane n/a 334 352
low_complexity n/a 371 395
transmembrane n/a 372 396
transmembrane n/a 463 482
low_complexity n/a 464 475
transmembrane n/a 488 507
low_complexity n/a 518 531
transmembrane n/a 519 545
transmembrane n/a 551 568
Pfam CBS 601 645
disorder n/a 644 645
disorder n/a 670 683
disorder n/a 686 698
disorder n/a 700 702
disorder n/a 705 708
disorder n/a 716 718
disorder n/a 721 729
disorder n/a 771 772
Pfam CBS 801 857

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P51797. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAGCRGSLCC CCRWCCCCGE RETRTPEELT ILGETQEEED EILPRKDYES
50
51
LDYDRCINDP YLEVLETMDN KKGRRYEAVK WMVVFAIGVC TGLVGLFVDF
100
101
FVRLFTQLKF GVVQTSVEEC SQKGCLALSL LELLGFNLTF VFLASLLVLI
150
151
EPVAAGSGIP EVKCYLNGVK VPGIVRLRTL LCKVLGVLFS VAGGLFVEKE
200
201
GPMIHSGSVV GAGLPQFQSI SLRKIQFNFP YFRSDRDKRD FVSAGAAAGV
250
251
AAAFGAPIGG TLFSLEEGSS FWNQGLTWKV LFCSMSATFT LNFFRSGIQF
300
301
GSWGSFQLPG LLNFGEFKCS DSDKKCHLWT AMDLGFFVVM GVIGGLLGAT
350
351
FNCLNKRLAK YRMRNVHPKP KLVRVLESLL VSLVTTVVVF VASMVLGECR
400
401
QMSSSSQIGN DSFQLQVTED VNSSIKTFFC PNDTYNDMAT LFFNPQESAI
450
451
LQLFHQDGTF SPVTLALFFV LYFLLACWTY GISVPSGLFV PSLLCGAAFG
500
501
RLVANVLKSY IGLGHIYSGT FALIGAAAFL GGVVRMTISL TVILIESTNE
550
551
ITYGLPIMVT LMVAKWTGDF FNKGIYDIHV GLRGVPLLEW ETEVEMDKLR
600
601
ASDIMEPNLT YVYPHTRIQS LVSILRTTVH HAFPVVTENR GNEKEFMKGN
650
651
QLISNNIKFK KSSILTRAGE QRKRSQSMKS YPSSELRNMC DEHIASEEPA
700
701
EKEDLLQQML ERRYTPYPNL YPDQSPSEDW TMEERFRPLT FHGLILRSQL
750
751
VTLLVRGVCY SESQSSASQP RLSYAEMAED YPRYPDIHDL DLTLLNPRMI
800
801
VDVTPYMNPS PFTVSPNTHV SQVFNLFRTM GLRHLPVVNA VGEIVGIITR
850
851
HNLTYEFLQA RLRQHYQTI                                  
869
 

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Checksums:
CRC64:D625F0C2189EB6F7
MD5:fde1c728f013aedc55875da2d20488f0

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.