Summary
This is the summary of UniProt entry CASP6_HUMAN (P55212).
Description: | Caspase-6 |
Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
|
Length: | 293 amino acids |
Reference Proteome: |
![]() |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
Download the data used to generate the domain graphic in JSON format.
Show or hide the data used to generate the graphic in JSON format.
Source | Domain | Start | End |
---|---|---|---|
disorder | n/a | 1 | 16 |
disorder | n/a | 18 | 19 |
Pfam | Peptidase_C14 | 44 | 287 |
Show or hide domain scores.
Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession P55212. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
Sequence: | 1
MSSASGLRRG HPAGGEENMT ETDAFYKREM FDPAEKYKMD HRRRGIALIF
50 51
NHERFFWHLT LPERRGTCAD RDNLTRRFSD LGFEVKCFND LKAEELLLKI
100 101
HEVSTVSHAD ADCFVCVFLS HGEGNHIYAY DAKIEIQTLT GLFKGDKCHS
150 151
LVGKPKIFII QACRGNQHDV PVIPLDVVDN QTEKLDTNIT EVDAASVYTL
200 201
PAGADFLMCY SVAEGYYSHR ETVNGSWYIQ DLCEMLGKYG SSLEFTELLT
250 251
LVNRKVSQRR VDFCKDPSAI GKKQVPCFAS MLTKKLHFFP KSN
293
Show the unformatted sequence. |
Checksums: |
CRC64:0738AE4F9791EBD7
MD5:0154cd5c66753743489b7aedc1771b6f
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
The parts of the structure corresponding to the Pfam family are highlighted in yellow.
Loading Structure Data
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.