Summary
This is the summary of UniProt entry CAD13_HUMAN (P55290).
| Description: | Cadherin-13 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
|
| Length: | 713 amino acids |
| Reference Proteome: |
|
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
Download the data used to generate the domain graphic in JSON format.
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| Source | Domain | Start | End |
|---|---|---|---|
| sig_p | n/a | 1 | 22 |
| low_complexity | n/a | 7 | 19 |
| Pfam | Cadherin_pro | 26 | 112 |
| Pfam | Cadherin | 143 | 236 |
| disorder | n/a | 156 | 163 |
| disorder | n/a | 166 | 168 |
| disorder | n/a | 170 | 178 |
| disorder | n/a | 184 | 187 |
| disorder | n/a | 231 | 232 |
| disorder | n/a | 247 | 252 |
| Pfam | Cadherin | 250 | 354 |
| disorder | n/a | 255 | 258 |
| disorder | n/a | 262 | 270 |
| disorder | n/a | 281 | 288 |
| disorder | n/a | 293 | 300 |
| disorder | n/a | 350 | 351 |
| disorder | n/a | 354 | 356 |
| disorder | n/a | 362 | 367 |
| Pfam | Cadherin | 368 | 469 |
| disorder | n/a | 383 | 384 |
| disorder | n/a | 396 | 399 |
| disorder | n/a | 409 | 418 |
| disorder | n/a | 452 | 456 |
| Pfam | Cadherin | 483 | 576 |
| disorder | n/a | 569 | 572 |
| Pfam | Cadherin | 588 | 680 |
| low_complexity | n/a | 695 | 713 |
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession P55290. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MQPRTPLVLC VLLSQVLLLT SAEDLDCTPG FQQKVFHINQ PAEFIEDQSI
50 51
LNLTFSDCKG NDKLRYEVSS PYFKVNSDGG LVALRNITAV GKTLFVHART
100 101
PHAEDMAELV IVGGKDIQGS LQDIFKFART SPVPRQKRSI VVSPILIPEN
150 151
QRQPFPRDVG KVVDSDRPER SKFRLTGKGV DQEPKGIFRI NENTGSVSVT
200 201
RTLDREVIAV YQLFVETTDV NGKTLEGPVP LEVIVIDQND NRPIFREGPY
250 251
IGHVMEGSPT GTTVMRMTAF DADDPATDNA LLRYNIRQQT PDKPSPNMFY
300 301
IDPEKGDIVT VVSPALLDRE TLENPKYELI IEAQDMAGLD VGLTGTATAT
350 351
IMIDDKNDHS PKFTKKEFQA TVEEGAVGVI VNLTVEDKDD PTTGAWRAAY
400 401
TIINGNPGQS FEIHTNPQTN EGMLSVVKPL DYEISAFHTL LIKVENEDPL
450 451
VPDVSYGPSS TATVHITVLD VNEGPVFYPD PMMVTRQEDL SVGSVLLTVN
500 501
ATDPDSLQHQ TIRYSVYKDP AGWLNINPIN GTVDTTAVLD RESPFVDNSV
550 551
YTALFLAIDS GNPPATGTGT LLITLEDVND NAPFIYPTVA EVCDDAKNLS
600 601
VVILGASDKD LHPNTDPFKF EIHKQAVPDK VWKISKINNT HALVSLLQNL
650 651
NKANYNLPIM VTDSGKPPMT NITDLRVQVC SCRNSKVDCN AAGALRFSLP
700 701
SVLLLSLFSL ACL
713
Show the unformatted sequence. |
| Checksums: |
CRC64:CEB662D77824CB60
MD5:bac7e3ea08b45fa3bd8de4dc17f2fb65
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
| Pfam family | UniProt residues | PDB ID | PDB chain ID | PDB residues | View |
|---|---|---|---|---|---|
| Cadherin | 143 - 236 | 2V37 | A | 5 - 98 | Show 3D Structure View in InterPro |
The parts of the structure corresponding to the Pfam family are highlighted in blue.
Loading Structure Data
AlphaFold Structure Prediction
The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.
Model confidence scale
| Very High (pLDDT > 90) | |
| Confident (90 > pLDDT > 70) | |
| Low (70 > pLDDT > 50) | |
| Very Low (pLDDT < 50) |
